Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512048 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL23182183 | 0.85 | KDM4E (0.70) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14468540 | 0.81 | KDM4E (0.66) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL30223594 | 0.80 | KDM4E (0.73) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL28949453 | 0.80 | KDM4E (0.73) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL28949451 | 0.80 | KDM4E (0.73) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL15538757 | 0.77 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL12174984 | 0.76 | SCN4A (0.62) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL5567542 | 0.76 | SCN4A (0.62) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL12174911 | 0.76 | SCN4A (0.62) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666766-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | Taisho Pharmaceutical Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |