SCHEMBL1446935

SCHEMBL1446935

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nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 15/20 0.42
DPP8 Q6V1X1 9/20 0.42
DPP9 Q86TI2 8/20 0.42
SLC7A5 Q01650 1/20 0.39
DPP7 Q9UHL4 8/20 0.38
IARS1 P41252 1/20 0.35
FAP Q12884 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28044917 1.00 DPP4 (0.42) DPP4DPP8DPP9SLC7A5DPP7
SCHEMBL5161688 0.94 DPP4 (0.46) DPP4DPP8DPP9DPP7IARS1
SCHEMBL3930248 0.94 DPP4 (0.46) DPP4DPP8DPP9DPP7IARS1
Threonine SCHEMBL4616599 0.88 SLC7A5 (0.44) DPP4DPP8DPP9SLC7A5DPP7
SCHEMBL1537392 0.88 DPP4 (0.42) DPP4DPP8DPP9DPP7IARS1
SCHEMBL1537362 0.88 DPP4 (0.42) DPP4DPP8DPP9DPP7IARS1
SCHEMBL2052320 0.86 DPP4 (0.41) DPP4DPP8DPP9DPP7IARS1
SCHEMBL288204 0.84 SLC7A5 (0.52) DPP4DPP8DPP9SLC7A5DPP7
SCHEMBL10530419 0.84 SLC7A5 (0.52) DPP4DPP8DPP9SLC7A5DPP7
SCHEMBL27932393 0.84 SLC7A5 (0.52) DPP4DPP8DPP9SLC7A5DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10626156-B2 Bioreversable promoieties for nitrogen-containing and hydroxyl-containing drugs Han, Jie (US) 2020-04-21 US claimed
US-20180296522-A1 ENHANCED EXPRESSION OF mTOR AND INHIBITED EXPRESSION OF MYOSTATIN IN SKELETAL MUSCLE CELLS IN INGREDIENTS, INC. (US) 2018-10-18 US claimed
WO-2016073843-A2 ENHANCED EXPRESSION OF MTOR AND INHIBITED EXPRESSION OF MYOSTATIN IN SKELETAL MUSCLE CELLS IN INGREDIENTS, INC. (US) 2016-05-12 WO claimed
EP-2366786-A2 Cytokine receptor modulators and uses thereof VALORISATION HSJ, Société en Commandite (CA) 2011-09-21 EP claimed
EP-2245148-A1 CELLULASE VARIANTS WITH REDUCED INHIBITION BY GLUCOSE Iogen Energy Corporation (CA) 2010-11-03 EP claimed
US-20090186381-A1 CELLULASE VARIANTS WITH REDUCED INHIBITION BY GLUCOSE IOGEN ENERGY CORPORATION (CA) 2009-07-23 US claimed
WO-2009089630-A1 CELLULASE VARIANTS WITH REDUCED INHIBITION BY GLUCOSE IOGEN ENERGY CORPORATION (CA) 2009-07-23 WO claimed
EP-1885855-A4 CYTOKINE RECEPTOR MODULATORS AND USES THEREOF VALORISATION HSJ SOC EN COMMAN (CA) 2009-03-04 EP claimed
US-20090048161-A1 Cytokine receptor modulators and uses thereof VALORISATION HSJ, SOCIETE EN COMMANDITE (CA) 2009-02-19 US claimed
US-20090018196-A1 FOOD COMPOSITION COMPRISING AMINO ACIDS INNOVAFOOD AB (SE) 2009-01-15 US claimed
EP-1414431-B1 AMINO-ACID-BASED therapeutic COMPOSITIONS, FOR THE HEALING AND/OR MENDING OF WOUNDS AND LESIONS, IN PARTICULAR IN THE OPHTHALMIC FIELD SOLARTIUM ENTPR LTD (IE) 2008-07-16 EP claimed
EP-1885855-A2 CYTOKINE RECEPTOR MODULATORS AND USES THEREOF VALORISATION HSJ, Société en Commandite (CA) 2008-02-13 EP claimed
WO-2007004060-A2 CYTOKINE RECEPTOR MODULATORS AND USES THEREOF VALORISATION HSJ, SOCIETE EN COMMANDITE (CA) 2007-01-11 WO claimed
US-6342243-B1 ORALLY ADMINISTERING AN AMINO ACID AND/OR A PEPTIDE TO A NEONATAL RUMINANT FOR A PERIOD OF FROM A DAY AFTER SAID RUMINANT'S BIRTH UNTIL THE FUNCTION OF THE RUMEN DEVELOPS. AJINOMOTO CO., INC. (JP) 2002-01-29 US claimed
CN-113122521-B Polypeptides having lipase activity and uses thereof 丰益国际有限公司 2024-05-14 CN disclosed
CN-117165545-A Alpha-isopropyl malate synthase mutant, recombinant microorganism and application thereof 胡丹 2023-12-05 CN disclosed
CN-117137977-A Preparation method of lactation-promoting traditional Chinese medicine composition for sows 北京中农劲腾生物制药股份有限公司 2023-12-01 CN disclosed
US-4508823-A GENETIC ENGINEERING-CHROMOSOMAL DNA SPLITTING WITH ENZYME, THEN JOINING TO HGIVE PLASMID/- MICROLIFE TECHNICS, INC. (US) 1985-04-02 US disclosed
US-4391907-A GENETIC ENGINEERING AJINOMOTO COMPANY INCORPORATED (JP) 1983-07-05 US disclosed
EP-0030727-A2 Method for producing L-valine by fermentation and method for producing a new microorganism of the genus Escherichia AJINOMOTO CO., INC. (JP) 1981-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626156-B2 Bioreversable promoieties for nitrogen-containing and hydroxyl-containing drugs NOS2, EGLN2, HPGD DPP4 1564/4885DPP8 1691/4885DPP9 1143/4885
US-20180296522-A1 ENHANCED EXPRESSION OF mTOR AND INHIBITED EXPRESSION OF MYOSTATIN IN SKELETAL MUSCLE CELLS MSTN, MTPN, MTOR DPP4 3235/4885DPP8 1545/4885DPP9 2386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.