Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 19/20 | 0.70 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373409 | 0.92 | CXCR3 (0.81) | CXCR3CLK2DYRK1ACLK4 | |
| SCHEMBL14373414 | 0.91 | CXCR3 (0.79) | CXCR3 | |
| SCHEMBL14373410 | 0.91 | CXCR3 (0.70) | CXCR3 | |
| SCHEMBL14470687 | 0.90 | CXCR3 (0.86) | CXCR3 | |
| SCHEMBL14470434 | 0.88 | CXCR3 (0.87) | CXCR3 | |
| SCHEMBL14373845 | 0.85 | CXCR3 (0.94) | CXCR3CLK2DYRK1ACLK4 | |
| SCHEMBL14373407 | 0.83 | CXCR3 (0.93) | CXCR3 | |
| SCHEMBL14373442 | 0.83 | CXCR3 (0.79) | CXCR3CLK2DYRK1ACLK4 | |
| SCHEMBL14373415 | 0.83 | CXCR3 (0.65) | CXCR3 | |
| SCHEMBL14470538 | 0.83 | CXCR3 (0.61) | CXCR3CLK2DYRK1ACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |