Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 17/20 | 0.61 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373645 | 0.91 | CXCR3 (0.74) | CXCR3CLK2DYRK1ACLK4MEN1 | |
| SCHEMBL14373639 | 0.90 | CXCR3 (0.64) | CXCR3MEN1KMT2A | |
| SCHEMBL14373649 | 0.89 | CXCR3 (0.61) | CXCR3CLK2DYRK1ACLK4KMT2A | |
| SCHEMBL14470436 | 0.83 | CXCR3 (0.70) | CXCR3CLK2DYRK1ACLK4 | |
| SCHEMBL14470688 | 0.81 | CXCR3 (0.86) | CXCR3 | |
| SCHEMBL14470687 | 0.81 | CXCR3 (0.86) | CXCR3 | |
| SCHEMBL5456451 | 0.81 | CXCR3 (0.77) | CXCR3CLK2DYRK1ACLK4MEN1 | |
| SCHEMBL14470441 | 0.80 | CXCR3 (0.65) | CXCR3CLK2DYRK1ACLK4MEN1 | |
| SCHEMBL14373646 | 0.80 | CXCR3 (0.56) | CXCR3CLK2DYRK1ACLK4 | |
| SCHEMBL14470434 | 0.79 | CXCR3 (0.87) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007084728-A2 | 2-IMINO-BENZIMIDAZOLES | ABBOTT LABORATORIES (US) | 2007-07-26 | — | — | WO | disclosed |