Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | TOP2A | P11388 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.70 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.60 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14471235 | 0.94 | ALDH1A1 (0.71) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10374013 | 0.94 | KDM4E (0.79) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL29576608 | 0.93 | ALDH1A1 (0.81) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL2780752 | 0.93 | ALDH1A1 (0.81) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10374148 | 0.91 | KDM4E (0.74) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10373193 | 0.91 | KDM4E (0.74) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10566738 | 0.90 | KDM4E (0.73) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL14453824 | 0.90 | KDM4E (0.70) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL14453829 | 0.86 | KDM4E (0.68) | ALDH1A1KDM4ELMNAHPGDHSD17B10 | |
| SCHEMBL10564197 | 0.86 | KDM4E (0.67) | ALDH1A1KDM4ELMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7250413-B2 | C-25 carbamate rifamycin derivatives with activity against drug-resistant microbes | CUMBRE PHARMACEUTICALS INC. (US) | 2007-07-31 | — | — | US | disclosed |