SCHEMBL2780752

SCHEMBL2780752

CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.81
KDM4E B2RXH2 5/20 0.81
LMNA P02545 4/20 0.79
HPGD P15428 3/20 0.79
HSD17B10 Q99714 2/20 0.79
MAPT P10636 1/20 0.79
CYP1A2 P05177 1/20 0.77
TOP2A P11388 1/20 0.77
CYP2C9 P11712 1/20 0.77
TOP2B Q02880 1/20 0.77
DRD3 P35462 1/20 0.69
PIK3CG P48736 7/20 0.65
PIK3CD O00329 5/20 0.65
PIK3R1 P27986 5/20 0.65
PIK3CA P42336 5/20 0.65
MEN1 O00255 2/20 0.65
KMT2A Q03164 2/20 0.65
NPC1 O15118 1/20 0.63
HTT P42858 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29576608 1.00 ALDH1A1 (0.81) ALDH1A1KDM4ELMNAHPGDHSD17B10
SCHEMBL14471237 0.93 ALDH1A1 (0.74) ALDH1A1KDM4ELMNAHPGDHSD17B10
SCHEMBL13694077 0.91 ALDH1A1 (0.71) ALDH1A1KDM4ELMNAHPGDHSD17B10
SCHEMBL9267263 0.91 ALDH1A1 (0.67) ALDH1A1KDM4ELMNAHPGDHSD17B10
SCHEMBL9265472 0.91 ALDH1A1 (0.70) ALDH1A1KDM4ELMNAHPGDHSD17B10
SCHEMBL9268053 0.91 ALDH1A1 (0.67) ALDH1A1KDM4ELMNAHPGDHSD17B10
SCHEMBL10736589 0.90 KDM4E (0.79) ALDH1A1KDM4ELMNAHPGDHSD17B10
SCHEMBL10374013 0.90 KDM4E (0.79) ALDH1A1KDM4ELMNAHPGDHSD17B10
SCHEMBL14159326 0.90 KDM4E (0.82) ALDH1A1KDM4ELMNAHPGDHSD17B10
SCHEMBL9145542 0.90 KDM4E (0.82) ALDH1A1KDM4ELMNAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775114-B1 PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS PROCTER & GAMBLE (US) 2000-03-22 EP claimed
US-5703231-A Process for making antimicrobial compounds THE PROCTER & GAMBLE COMPANY (US) 1997-12-30 US claimed
WO-1996004247-A1 PROCESS FOR MAKING ANTIMICROBIAL COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1996-02-15 WO claimed
US-5095112-A PROCESS FOR THE PREPARATION OF QUINOLONECARBOXYLIC ACID ESTERS BAYER AKTIENGESELLSCHAFT (DE) 1992-03-10 US claimed
US-4670444-A 7-amino-1-cyclopropyl-4-oxo-1, 4-dihydro-quinoline-and naphthyridine-3-carboxylic acids and antibacterial agents containing these compounds BAYER AKTIENGESELLSCHAFT (DE) 1987-06-02 US claimed
EP-0078362-B1 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-PIPERAZINO-QUINOLINE-3-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS CONTAINING THEM BAYER AG (DE) 1986-10-22 EP claimed
US-4563459-A FUNGICIDES AND BACTERICIDES FOR AGRICULTURAL USE BAYER AKTIENGESELLSCHAFT (DE) 1986-01-07 US claimed
EP-0078362-A2 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-quinoline-3-carboxylic acids, process for their preparation and antibacterial agents containing them BAYER AG (DE) 1983-05-11 EP claimed
US-20250313561-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2025-10-09 US disclosed
US-12344606-B2 Next-generation modulators of stimulator of interferon genes (STING) Ryvu Therapeutics S.A. (PL) 2025-07-01 US disclosed
EP-3983078-B1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2023-11-15 EP disclosed
EP-3983078-B1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) RYVU THERAPEUTICS S A (PL) 2023-11-15 EP disclosed
WO-2023077126-A1 TRANS-CYCLOOCTENE CONJUGATES TAMBO, INC. (US) 2023-05-04 WO disclosed
US-20220251082-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) Ryvu Therapeutics S.A. (PL) 2022-08-11 US disclosed
EP-0191185-A1 Quinoline-carboxylic acid derivatives DAIICHI SEIYAKU CO., LTD. (JP) 1986-08-20 EP disclosed
EP-0113091-B1 MICROBIOCIDAL AGENTS BASED ON QUINOLONE-CARBOXYLIC ACIDS BAYER AG (DE) 1986-07-30 EP disclosed
US-4563459-A FUNGICIDES AND BACTERICIDES FOR AGRICULTURAL USE BAYER AKTIENGESELLSCHAFT (DE) 1986-01-07 US disclosed
EP-0113091-A1 Microbiocidal agents based on quinolone-carboxylic acids BAYER AG (DE) 1984-07-11 EP disclosed
EP-0078362-A2 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-quinoline-3-carboxylic acids, process for their preparation and antibacterial agents containing them BAYER AG (DE) 1983-05-11 EP disclosed
EP-0078362-A2 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino-quinoline-3-carboxylic acids, process for their preparation and antibacterial agents containing them BAYER AG (DE) 1983-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251082-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) STING1, IRF3, CGAS ALDH1A1 4562/4885KDM4E 4160/4885LMNA 3293/4885
US-12344606-B2 Next-generation modulators of stimulator of interferon genes (STING) STING1, IRF3, CGAS ALDH1A1 4562/4885KDM4E 4160/4885LMNA 3293/4885
US-20250313561-A1 NEXT-GENERATION MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) STING1, IRF3, CGAS ALDH1A1 4562/4885KDM4E 4160/4885LMNA 3293/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.