SCHEMBL14473602

SCHEMBL14473602

CCC(C)(CI)c1cccc(Oc2ccc(C(c3ccc(OC(C)(CC)c4cccc(Cl)c4C#N)cc3)(C(F)(F)F)C(F)(F)F)cc2)c1C#N

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.35
TLR8 Q9NR97 1/20 0.34
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.33
CNR1 P21554 1/20 0.33
GPR183 P32249 1/20 0.33
CNR2 P34972 1/20 0.33
KMT2A Q03164 1/20 0.33
AR P10275 1/20 0.32
BCL2L1 Q07817 1/20 0.30
MCL1 Q07820 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12872885 0.91 HSD11B1 (0.41) HSD11B1TLR8MAPTMEN1CNR1
SCHEMBL13342162 0.89 HSD11B1 (0.37) HSD11B1TLR8MAPTMEN1CNR1
SCHEMBL17750837 0.89 HSD11B1 (0.36) HSD11B1TLR8MAPTMEN1CNR1
SCHEMBL14629708 0.89 HSD11B1 (0.36) HSD11B1TLR8MAPTMEN1CNR1
SCHEMBL13274032 0.85 HSD11B1 (0.37) HSD11B1TLR8MAPTMEN1CNR1
SCHEMBL17778617 0.84 HSD11B1 (0.37) HSD11B1TLR8MAPTMEN1CNR1
SCHEMBL14781016 0.84 HSD11B1 (0.33) HSD11B1TLR8MAPTMEN1CNR1
SCHEMBL13298968 0.84 MAPT (0.38) HSD11B1TLR8MAPTMEN1CNR1
SCHEMBL12969339 0.84 HSD11B1 (0.36) HSD11B1TLR8MAPTMEN1CNR1
SCHEMBL21423191 0.83 MAPT (0.39) HSD11B1TLR8MAPTMEN1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070166588-A1 Membrane-electrode assembly for solid polymer electrolyte fuel cell and method for producing the same HONDA MOTOR CO., LTD. 2007-07-19 US disclosed