Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | VDR | P11473 | 7/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039872 | 0.86 | CYP19A1 (0.45) | CYP19A1VDR | |
| SCHEMBL13243996 | 0.86 | CYP19A1 (0.45) | CYP19A1VDR | |
| SCHEMBL19773983 | 0.86 | CYP19A1 (0.45) | CYP19A1VDR | |
| SCHEMBL12600213 | 0.86 | CYP19A1 (0.45) | CYP19A1VDR | |
| SCHEMBL8992693 | 0.78 | CYP19A1 (0.36) | CYP19A1VDR | |
| SCHEMBL8992696 | 0.78 | CYP19A1 (0.36) | CYP19A1VDR | |
| SCHEMBL3258798 | 0.76 | VDR (0.41) | CYP19A1VDR | |
| SCHEMBL3258795 | 0.76 | VDR (0.41) | CYP19A1VDR | |
| SCHEMBL3297400 | 0.76 | VDR (0.41) | CYP19A1VDR | |
| SCHEMBL8992724 | 0.75 | CYP19A1 (0.39) | CYP19A1VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244719-B2 | 2-methylene-19,26,27-trinor-(20S)-1α-hydroxyvitamin D3 and its uses | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-07-17 | — | — | US | disclosed |