Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.32 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL984488 | 0.80 | LMNA (0.36) | LMNAALKBH5SUCNR1EGLN1CYP1A2 | |
| SCHEMBL12227935 | 0.77 | ALDH1A1 (0.36) | LMNAALKBH5SUCNR1EGLN1CYP1A2 | |
| SCHEMBL10215089 | 0.75 | LMNA (0.40) | LMNAALKBH5SUCNR1EGLN1THRB | |
| SCHEMBL14953522 | 0.74 | CYP1A2 (0.38) | LMNAALKBH5SUCNR1EGLN1CYP1A2 | |
| SCHEMBL14343340 | 0.73 | LMNA (0.38) | LMNAALKBH5SUCNR1EGLN1KMT2A | |
| SCHEMBL22791486 | 0.72 | ALDH1A1 (0.33) | CYP1A2THRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL12227736 | 0.72 | ALDH1A1 (0.33) | CYP1A2THRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL510917 | 0.71 | LMNA (0.36) | LMNAALKBH5SUCNR1EGLN1ALDH1A1 | |
| SCHEMBL4638213 | 0.71 | ALDH1A1 (0.40) | LMNAALKBH5SUCNR1EGLN1ALDH1A1 | |
| SCHEMBL9883735 | 0.71 | ALDH1A1 (0.37) | LMNAALKBH5SUCNR1EGLN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013000970-A1 | BIS TRIDENTATE W3O2 CLUSTERS FOR X-RAY IMAGING | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-03 | — | — | WO | disclosed |