SCHEMBL14474432

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20273295	0.93	ABCG2 (0.58)	ABCG2ABCB1EPHA2KDREPHB4
	SCHEMBL14474473	0.92	ABCG2 (0.57)	ABCG2ABCB1EPHA2KDREPHB4
	SCHEMBL14474459	0.89	ABCG2 (0.56)	ABCG2ABCB1EPHA2KDREPHB4
	SCHEMBL14474004	0.89	ABCG2 (0.63)	ABCG2ABCB1EPHA2KDREPHB4
	SCHEMBL14474855	0.88	EPHA2 (0.61)	ABCG2ABCB1EPHA2KDREPHB4
	SCHEMBL16183268	0.88	ABCG2 (0.59)	ABCG2ABCB1USP2MEN1KMT2A
	SCHEMBL14474417	0.86	EPHA2 (0.61)	ABCG2ABCB1EPHA2KDREPHB4
	SCHEMBL14474871	0.85	ABCG2 (0.63)	ABCG2ABCB1EPHA2KDREPHB4
	SCHEMBL14474465	0.83	ABCG2 (0.59)	ABCG2ABCB1USP2MEN1KMT2A
	SCHEMBL14474881	0.82	CYP1A2 (0.57)	ABCG2ABCB1USP2MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.