SCHEMBL14475409

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14475398	0.87	MAPT (0.54)	ABCG2TSHRMAPTMAPK1CYP1A2
	SCHEMBL14474136	0.83	CYP1A2 (0.56)	ABCG2TSHRMAPTMAPK1CYP1A2
	SCHEMBL14474881	0.83	CYP1A2 (0.57)	ABCG2TSHRMAPTMAPK1CYP1A2
	SCHEMBL19196907	0.80	ABCG2 (0.70)	ABCG2TSHRMAPTMAPK1CYP1A2
	SCHEMBL14475400	0.80	ABCG2 (0.55)	ABCG2TSHRMAPTMAPK1CYP1A2
	SCHEMBL14474450	0.78	ABCG2 (0.59)	ABCG2TSHRMAPTMAPK1CYP1A2
	SCHEMBL14726136	0.78	ABCG2 (0.72)	ABCG2PDE5A
	SCHEMBL14726741	0.78	MAPK1 (0.53)	ABCG2TSHRMAPTMAPK1CYP1A2
	SCHEMBL14473992	0.78	CYP1A2 (0.57)	ABCG2TSHRMAPTMAPK1CYP1A2
	SCHEMBL14473979	0.77	ABCG2 (0.59)	ABCG2TSHRMAPTMAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.