Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13184542 | 1.00 | CASP3 (0.53) | CASP3KMT2APIN1MDM4TP53 | |
| SCHEMBL13165057 | 1.00 | CASP3 (0.53) | CASP3KMT2APIN1MDM4TP53 | |
| SCHEMBL13184539 | 0.88 | CASP3 (0.46) | CASP3KMT2APIN1MDM4TP53 | |
| SCHEMBL13165055 | 0.88 | CASP3 (0.46) | CASP3KMT2APIN1MDM4TP53 | |
| SCHEMBL5201071 | 0.87 | CASP3 (0.53) | CASP3KMT2APIN1MDM4TP53 | |
| SCHEMBL13165049 | 0.84 | CASP3 (0.40) | CASP3KMT2AEPHX2 | |
| SCHEMBL29670306 | 0.84 | CASP3 (0.55) | CASP3KMT2APIN1MDM4TP53 | |
| SCHEMBL22457542 | 0.84 | CASP3 (0.55) | CASP3KMT2APIN1MDM4TP53 | |
| SCHEMBL29609769 | 0.79 | CASP3 (0.55) | CASP3KMT2APIN1MDM4TP53 | |
| SCHEMBL24201195 | 0.79 | CASP3 (0.58) | CASP3KMT2APIN1MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130005943-A1 | Methods for Preparing Internally Constrained Peptides and Peptidomimetics | ARORA PARAMJIT (US) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005943-A1 | Methods for Preparing Internally Constrained Peptides and Peptidomimetics | VIP, IAPP, PTMA | CASP3 1153/4885KMT2A 4780/4885PIN1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.