Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5205166 | 0.90 | CASP3 (0.48) | CASP3KMT2ACTSLCTSBCTSS | |
| SCHEMBL27571135 | 0.90 | CASP3 (0.48) | CASP3KMT2ACTSLCTSBCTSS | |
| SCHEMBL13184542 | 0.87 | CASP3 (0.53) | CASP3KMT2ACTSLCTSBCTSS | |
| SCHEMBL13165057 | 0.87 | CASP3 (0.53) | CASP3KMT2ACTSLCTSBCTSS | |
| SCHEMBL14477381 | 0.87 | CASP3 (0.53) | CASP3KMT2ACTSLCTSBCTSS | |
| SCHEMBL29670306 | 0.86 | CASP3 (0.55) | CASP3KMT2ACTSLCTSBCTSS | |
| SCHEMBL22457542 | 0.86 | CASP3 (0.55) | CASP3KMT2ACTSLCTSBCTSS | |
| SCHEMBL5201715 | 0.84 | CASP3 (0.44) | CASP3KMT2ACTSLCTSBCTSS | |
| SCHEMBL5201718 | 0.84 | CASP3 (0.44) | CASP3KMT2ACTSLCTSBCTSS | |
| SCHEMBL27561296 | 0.84 | CASP3 (0.44) | CASP3KMT2ACTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400521-B1 | PIPERAZINE COMPOUNDS | KOWA CO (JP) | 2007-11-07 | — | — | EP | disclosed |