Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 6/20 | 0.38 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478659 | 0.91 | AXL (0.37) | KDM4EMAPK10AXLCDK8NPC1 | |
| SCHEMBL14478648 | 0.86 | ACVR1 (0.41) | KDM4EMAPK10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20624076 | 0.84 | MEN1 (0.44) | KDM4ENPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL20623678 | 0.84 | MEN1 (0.44) | KDM4ENPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL20623633 | 0.84 | MEN1 (0.44) | KDM4ENPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL20623681 | 0.84 | L3MBTL1 (0.45) | KDM4ENPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL20624074 | 0.84 | L3MBTL1 (0.45) | KDM4ENPC1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL14478673 | 0.84 | ADORA2A (0.40) | KDM4ENPC1RAB9ASMN1; SMN2MET | |
| SCHEMBL14478631 | 0.83 | TOP1 (0.40) | KDM4ESMN1; SMN2NFKB1LMNAMAPT | |
| SCHEMBL20624440 | 0.81 | MEN1 (0.40) | KDM4ENPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8986855-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-03-24 | — | — | US | disclosed |
| US-8986855-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2015-03-24 | — | — | US | disclosed |
| US-8951649-B2 | — | — | 2015-02-10 | — | — | US | disclosed |
| US-8951649-B2 | — | — | 2015-02-10 | — | — | US | disclosed |
| US-20130001529-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2013-01-03 | — | — | US | disclosed |
| US-20130001529-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130001529-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CRY1, ORC3, NR2E3 | KDM4E 2671/4885MAPK10 3789/4885AXL 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.