Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.54 |
| ▸ | CTSG | P08311 | 7/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 7/20 | 0.54 |
| ▸ | CMA1 | P23946 | 7/20 | 0.54 |
| ▸ | CTSL | P07711 | 5/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.48 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14479055 | 0.82 | CTSL (0.51) | CTSGCTRB1CTSLCTSSCTSK | |
| SCHEMBL14479056 | 0.82 | CTSL (0.56) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL14479041 | 0.81 | CTSL (0.52) | CTSGCTRB1CTSLCTSSCTSK | |
| SCHEMBL13673291 | 0.78 | CTSL (0.58) | CTSGCTRB1CTSLCTSSCTSK | |
| SCHEMBL11276525 | 0.76 | ACE (0.68) | CTSLCTSSCTSK | |
| SCHEMBL13669573 | 0.75 | GAA (0.69) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL4369272 | 0.75 | GAA (0.69) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL13673427 | 0.73 | CTSL (0.60) | CTRB1CTSLCTSSCTSKPSMB5 | |
| SCHEMBL16694897 | 0.73 | PSMB5 (0.61) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL16694898 | 0.73 | PSMB5 (0.61) | CTSLCTSSCTSKPSMB5GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957555-A1 | METHOD FOR MODIFYING DERIVATIVES OF AMINO ACIDS AND PEPTIDES, COMPOUNDS PRODUCED, AND USE | Consejo Superior De Investigaciones Científicas (CSIC) (ES) | 2015-12-23 | — | — | EP | disclosed |
| WO-2014125145-A1 | METHOD FOR MODIFYING DERIVATIVES OF AMINO ACIDS AND PEPTIDES, COMPOUNDS PRODUCED, AND USE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2014-08-21 | — | — | WO | disclosed |
| WO-2013001120-A1 | CHEMICAL PROCESS FOR THE SELECTIVE MODIFICATION OF PEPTIDES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2013-01-03 | — | — | WO | disclosed |