Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 6/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14479041 | 0.89 | CTSL (0.52) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL14479042 | 0.82 | PRSS1 (0.54) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL14479056 | 0.82 | CTSL (0.56) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL13673291 | 0.81 | CTSL (0.58) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL13673427 | 0.77 | CTSL (0.60) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL11276525 | 0.75 | ACE (0.68) | CTSLCTSSCTSKGAARAB9A | |
| SCHEMBL13669573 | 0.74 | GAA (0.69) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL4369272 | 0.74 | GAA (0.69) | CTSLCTSSCTSKPSMB5GPR139 | |
| SCHEMBL16667786 | 0.74 | GAA (0.62) | CTSLCTSSCTSKPSMB5GAA | |
| SCHEMBL13673425 | 0.73 | GAA (0.65) | CTSLCTSSCTSKGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013001120-A1 | CHEMICAL PROCESS FOR THE SELECTIVE MODIFICATION OF PEPTIDES | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2013-01-03 | — | — | WO | disclosed |