Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 20/20 | 0.74 |
| ▸ | TRPV4 | Q9HBA0 | 7/20 | 0.63 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14479300 | 0.92 | TRPA1 (0.75) | TRPA1TRPV4TRPV3 | |
| SCHEMBL1802918 | 0.85 | TRPA1 (1.00) | TRPA1TRPV4TRPV3 | |
| SCHEMBL14479318 | 0.81 | TRPA1 (0.77) | TRPA1TRPV4TRPV3 | |
| SCHEMBL1797349 | 0.80 | TRPA1 (0.82) | TRPA1TRPV4TRPV3 | |
| SCHEMBL14479317 | 0.79 | TRPA1 (0.76) | TRPA1TRPV4TRPV3 | |
| SCHEMBL12652521 | 0.78 | TRPA1 (0.61) | TRPA1TRPV4 | |
| SCHEMBL14672007 | 0.78 | TRPA1 (0.71) | TRPA1TRPV4TRPV3 | |
| SCHEMBL1801930 | 0.78 | TRPA1 (1.00) | TRPA1TRPV4TRPV3 | |
| SCHEMBL12618019 | 0.77 | TRPA1 (0.59) | TRPA1TRPV4 | |
| SCHEMBL12292216 | 0.76 | TRPA1 (0.50) | TRPA1TRPV4TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012176105-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A TRPA1 ANTAGONIST AND A LEUKOTRIENE RECEPTOR ANTAGONIST | GLENMARK PHARMACEUTICALS SA (CH) | 2012-12-27 | — | — | WO | disclosed |