SCHEMBL14479554

SCHEMBL14479554

CCCCCCCCCC[C@H]1NC(=O)C1C

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 1/20 0.42
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HLCS P50747 1/20 0.39
GBA1 P04062 9/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12653853 1.00 FUCA1 (0.42) FUCA1ALDH1A1KDM4EMEN1MAPT
SCHEMBL12991554 0.98 ALDH1A1 (0.41) FUCA1ALDH1A1KDM4EMEN1MAPT
SCHEMBL17021214 0.92 ALDH1A1 (0.47) FUCA1ALDH1A1KDM4EMEN1MAPT
SCHEMBL19303363 0.76 ALDH1A1 (0.44) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL5811056 0.76 GBA1 (0.44) FUCA1GBA1GAA
SCHEMBL6561453 0.74 ABL1 (0.65) FUCA1ALDH1A1HPGDL3MBTL1HLCS
SCHEMBL30980779 0.74 ABL1 (0.65) FUCA1ALDH1A1HPGDL3MBTL1HLCS
SCHEMBL5442521 0.74 ALDH1A1 (0.45) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL10005090 0.74 ALDH1A1 (0.45) ALDH1A1KDM4EMEN1MAPTPKM
SCHEMBL14141054 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130004453-A1 NYLON-3 CO-POLYMERS AND SYNTHETIC LUNG SURFACTANT COMPOSITIONS CONTAINING SAME NATIONAL SCIENCE FOUNDATION 2013-01-03 US disclosed
US-20070087404-A1 Poly-beta-peptides from functionalized beta-lactam monomers and antibacterial compositions containing same WISCONSIN ALUMNI RESEARCH FOUNDATION 2007-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004453-A1 NYLON-3 CO-POLYMERS AND SYNTHETIC LUNG SURFACTANT COMPOSITIONS CONTAINING SAME SURF4, PLIN3, CLTB FUCA1 4697/4885ALDH1A1 4859/4885KDM4E 4706/4885
US-20070087404-A1 Poly-beta-peptides from functionalized beta-lactam monomers and antibacterial compositions containing same TMSB10, TMSB4X, PTMA FUCA1 4246/4885ALDH1A1 4840/4885KDM4E 2662/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.