Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 10/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12991554 | 0.78 | ALDH1A1 (0.41) | GBA1GAAFUCA1 | |
| SCHEMBL4174353 | 0.76 | — | — | |
| SCHEMBL12653853 | 0.76 | FUCA1 (0.42) | GBA1GAAFUCA1 | |
| SCHEMBL14479554 | 0.76 | FUCA1 (0.42) | GBA1GAAFUCA1 | |
| SCHEMBL19303363 | 0.76 | ALDH1A1 (0.44) | GBA1GAA | |
| SCHEMBL9073287 | 0.72 | ALDH1A1 (0.39) | GBA1 | |
| SCHEMBL21944971 | 0.72 | MAN2B1 (0.32) | — | |
| SCHEMBL5452034 | 0.72 | — | — | |
| SCHEMBL17021214 | 0.71 | ALDH1A1 (0.47) | GBA1FUCA1 | |
| SCHEMBL8998181 | 0.70 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1193252-B1 | Beta-Lactams useful for preparation of substituted isoserine esters using metal alkoxides | UNIV FLORIDA STATE (US) | 2006-12-27 | — | — | EP | disclosed |
| US-7074945-B2 | Metal alkoxide taxane derivatives | FLORIDA STATE UNIVERSITY (US) | 2006-07-11 | — | — | US | disclosed |
| EP-1146043-B1 | Taxanes having an alkyl substituted side-chain and pharmaceutical compositions containing them | UNIV FLORIDA STATE (US) | 2006-03-08 | — | — | EP | disclosed |
| EP-1260222-B1 | Pharmaceutical compositions containing new iso-butenyl substituted taxanes | UNIV FLORIDA STATE (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1227093-B1 | Beta-lactams useful for preparation of taxanes having furyl or thienyl substituted side-chain | UNIV FLORIDA STATE (US) | 2005-05-11 | — | — | EP | disclosed |
| EP-1260223-B1 | Taxanes having furyl or thienyl substituted side-chain | UNIV FLORIDA STATE (US) | 2005-05-11 | — | — | EP | disclosed |
| US-6878833-B2 | Tetraalkylammonium alkoxides | FLORIDA STATE UNIVERSITY (US) | 2005-04-12 | — | — | US | disclosed |
| US-6872842-B2 | Antileukemia and antitumor agents | FLORIDA STATE UNIVERSITY (US) | 2005-03-29 | — | — | US | disclosed |
| EP-1228759-B1 | Pharmaceutical compositions containing a taxane having a furyl or thienyl substituted side-chain | UNIV FLORIDA STATE (US) | 2004-12-15 | — | — | EP | disclosed |
| US-6797833-B2 | TAXANE DERIVATIVES HAVING A TRICYCLIC OR TETRACYCLIC CORE; REMARKABLE PROPERTIES IN VITRO; VALUABLE ANTILEUKEMIA, ANTITUMOR AND ANTICARCINOGENIC AGENTS; HUMAN CANCER CELL LINE COMPARABLE TO THAT OF TAXOL AND TAXOTERE | FLORIDA STATE UNIVERSITY | 2004-09-28 | — | — | US | disclosed |
| US-5254703-A | Semi-synthesis of taxane derivatives using metal alkoxides and oxazinones | FLORIDA STATE UNIVERSITY (US) | 1993-10-19 | — | — | US | disclosed |
| US-5229526-A | METAL ALKOXIDES | FLORIDA STATE UNIVERSITY (US) | 1993-07-20 | — | — | US | disclosed |
| WO-1993006094-A1 | METAL ALKOXIDES | FLORIDA STATE UNIVERSITY (US) | 1993-04-01 | — | — | WO | disclosed |
| WO-1993006079-A1 | PREPARATION OF SUBSTITUTED ISOSERINE ESTERS USING METAL ALKOXIDES AND β-LACTAMS | FLORIDA STATE UNIVERSITY (US) | 1993-04-01 | — | — | WO | disclosed |
| EP-0525589-A1 | Asymmetric synthesis of taxol side chain | Bristol-Myers Squibb Company (US) | 1993-02-03 | — | — | EP | disclosed |
| US-5175315-A | Reacting with alcohol in presence of altivating agent | FLORIDA STATE UNIVERSITY (US) | 1992-12-29 | — | — | US | disclosed |
| US-5136060-A | Reacting with alcohol | FLORIDA STATE UNIVERSITY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0428376-A1 | Method for preparation of taxol using an oxazinone | FLORIDA STATE UNIVERSITY (US) | 1991-05-22 | — | — | EP | disclosed |
| US-5015744-A | Esterification of an alcohol with an oxazinone | FLORIDA STATE UNIVERSITY (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0400971-A2 | Method for preparation of taxol | FLORIDA STATE UNIVERSITY (US) | 1990-12-05 | — | — | EP | disclosed |