Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vesticarpan SCHEMBL13731396 | 0.84 | MAOA (0.58) | MAPTMAPK1TDP1MAOAMAOB | |
| SCHEMBL14479684 | 0.81 | MAPT (0.68) | MAPTMAPK1TDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL31237481 | 0.81 | MAPT (0.80) | MAPTMAPK1TDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL12810803 | 0.81 | MAPT (0.80) | MAPTMAPK1TDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL29366996 | 0.81 | MAPT (0.80) | MAPTMAPK1TDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL12998414 | 0.81 | MAPT (0.80) | MAPTMAPK1TDP1MAOAMAOB | |
| Homopterocarpin SCHEMBL12810250 | 0.81 | MAPT (0.80) | MAPTMAPK1TDP1MAOAMAOB | |
| SCHEMBL14479679 | 0.81 | MAPT (0.61) | MAPTMAPK1TDP1MAOAMAOB | |
| SCHEMBL30523834 | 0.80 | MAOA (0.51) | MAPTMAPK1TDP1MAOAMAOB | |
| SCHEMBL12912390 | 0.79 | MAPT (0.70) | MAPTMAPK1TDP1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013000054-A1 | METHOD FOR PRODUCING PTEROCARPANS, CYTOMODULATING COMPOSITION CONTAINING PTEROCARPANS, AND USE OF PTEROCARPANS | UNIVERSIDADE FEDERAL DO CEARÁ - UFC (BR) | 2013-01-03 | — | — | WO | disclosed |