Vesticarpan

Vesticarpan

SCHEMBL13731396

COc1ccc2c(c1)OC1c3ccc(O)c(O)c3OCC21

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 2/20 0.58
▸ MAOB P27338 2/20 0.58
▸ MAPT P10636 2/20 0.57
▸ MAPK1 P28482 1/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ PTGS1 P23219 1/20 0.52
▸ PTPN1 P18031 3/20 0.50
▸ ALOX15 P16050 2/20 0.47
▸ ALOX12 P18054 2/20 0.47
▸ CYP3A4 P08684 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ USP2 O75604 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ TP53 P04637 1/20 0.41
▸ HPGD P15428 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ DRD2 P14416 1/20 0.40
▸ DRD3 P35462 1/20 0.40
▸ TYR P14679 1/20 0.39
▸ CYP19A1 P11511 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4727259 0.89 PTGS1 (0.63) MAOAMAOBMAPTMAPK1TDP1
SCHEMBL31357398 0.89 PTGS1 (0.63) MAOAMAOBMAPTMAPK1TDP1
SCHEMBL27836059 0.89 MAOA (0.73) MAOAMAOBMAPTMAPK1TDP1
SCHEMBL14479685 0.84 MAPT (0.56) MAOAMAOBMAPTMAPK1TDP1
Licoagrocarpin SCHEMBL30999863 0.82 PTPN1 (0.78) MAOAMAOBMAPTMAPK1TDP1
Licoagrocarpin SCHEMBL30999862 0.82 PTPN1 (0.78) MAOAMAOBMAPTMAPK1TDP1
Homopterocarpin SCHEMBL31237481 0.82 MAPT (0.80) MAOAMAOBMAPTMAPK1TDP1
Homopterocarpin SCHEMBL12810250 0.82 MAPT (0.80) MAOAMAOBMAPTMAPK1TDP1
Homopterocarpin SCHEMBL12998414 0.82 MAPT (0.80) MAOAMAOBMAPTMAPK1TDP1
Homopterocarpin SCHEMBL29366996 0.82 MAPT (0.80) MAOAMAOBMAPTMAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118695854-A Food-related particles, production method and production device 努利希尔有限公司 2024-09-24 — — CN disclosed
EP-4401711-A1 STABLE NON-AQUEOUS COMPOSITIONS OF FUNCTIONAL INGREDIENTS AND METHODS OF MAKING THE SAME Nulixir Inc. (US) 2024-07-24 — — EP disclosed
EP-4401712-A1 ORAL COMPOSITIONS WITH IMPROVED BIOAVAILABILITY AND METHODS OF MAKING THE SAME Nulixir Inc. (US) 2024-07-24 — — EP disclosed
EP-4401714-A1 ORAL COMPOSITIONS WITH PLANT MATTER EXTRACTS AND METHODS OF MAKING THE SAME Nulixir Inc. (US) 2024-07-24 — — EP disclosed
EP-4401713-A1 ALIMENTARY-RELATED PARTICLES, PRODUCTION METHODS, AND PRODUCTION APPARATUS Nulixir Inc. (US) 2024-07-24 — — EP disclosed
US-20240165036-A1 ENCAPSULATED VITAMIN D Nulixir Inc. 2024-05-23 — — US disclosed
US-20230404126-A1 ENCAPSULATED PRECURSORS OF NICOTINAMIDE ADENINE DINUCLEOTIDE AND METHODS OF MAKING THE SAME Nulixir Inc. 2023-12-21 — — US disclosed
US-20230157973-A1 ORAL COMPOSITIONS WITH PLANT MATTER EXTRACTS AND METHODS OF MAKING THE SAME Nulixir Inc. 2023-05-25 — — US disclosed
US-20230157963-A1 SOLID ORAL BEADS OF FUNCTIONAL INGREDIENTS AND METHODS OF MAKING THE SAME Nulixir Inc. 2023-05-25 — — US disclosed
US-20230149829-A1 ORAL COMPOSITIONS OF PLANTS THROUGH A DOUBLE EXTRACTION SYSTEM AND METHODS OF MAKING THE SAME Nulixir Inc. 2023-05-18 — — US disclosed
WO-2023043855-A1 ORAL COMPOSITIONS WITH PLANT MATTER EXTRACTS AND METHODS OF MAKING THE SAME Nulixir Inc. (US) 2023-03-23 — — WO disclosed
WO-2023043854-A1 ALIMENTARY-RELATED PARTICLES, PRODUCTION METHODS, AND PRODUCTION APPARATUS Nulixir Inc. (US) 2023-03-23 — — WO disclosed
US-20230082651-A1 STABLE AQUEOUS COMPOSITIONS OF PLANTS EXTRACTS AND METHODS OF MAKING THE SAME Nulixir Inc. 2023-03-16 — — US disclosed
US-20230079480-A1 STABLE NON-AQUEOUS COMPOSITIONS OF FUNCTIONAL INGREDIENTS AND METHODS OF MAKING THE SAME Nulixir Inc. 2023-03-16 — — US disclosed
US-20230081296-A1 STABLE NON-AQUEOUS COMPOSITIONS OF PLANTS EXTRACTS AND METHODS OF MAKING THE SAME Nulixir Inc. 2023-03-16 — — US disclosed
US-10292994-B2 Bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2019-05-21 — — US disclosed
EP-2705047-B1 BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS COUNCIL SCIENT IND RES (IN) 2015-08-05 — — EP disclosed
US-20140079834-A1 BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-03-20 — — US disclosed
EP-2705047-A1 BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS Council of Scientific and Industrial Research (IN) 2014-03-12 — — EP disclosed
WO-2012147102-A1 BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-11-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140079834-A1 BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS SOST, SHBG, ESR2 MAOA 4248/4885MAOB 2574/4885MAPT 4788/4885
US-10292994-B2 Bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders SOST, SHBG, ESR2 MAOA 4248/4885MAOB 2574/4885MAPT 4788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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