SCHEMBL144808

SCHEMBL144808

Cc1ccccc1[SiH](Cl)Cl

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
ACHE P22303 3/20 0.47
ALDH1A1 P00352 4/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CYP3A4 P08684 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
MGLL Q99685 1/20 0.33
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
ESR1 P03372 1/20 0.32
LMNA P02545 1/20 0.32
ALOX12 P18054 1/20 0.32
TAAR1 Q96RJ0 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9359908 0.85 TSHR (0.35) TSHRACHE
SCHEMBL9331644 0.85 TSHR (0.35) TSHRACHEALDH1A1
SCHEMBL7421898 0.83 TSHR (0.47) TSHRACHEALDH1A1CA1CA2
SCHEMBL11128898 0.83 MGLL (0.36) TSHRACHEALDH1A1CYP3A4TDP1
SCHEMBL27952763 0.81 TSHR (0.45) TSHRACHEALDH1A1CA1CA2
SCHEMBL25940620 0.80 TSHR (0.39) TSHRACHEALDH1A1CA1CA2
SCHEMBL9341909 0.79 TSHR (0.43) TSHRACHEALDH1A1CA1CA2
SCHEMBL21383259 0.79 TSHR (0.43) TSHRACHEALDH1A1CA1CA2
SCHEMBL2079047 0.79 TRPA1 (0.42) TSHRACHEALDH1A1CA1CA2
SCHEMBL9356901 0.77 TSHR (0.41) TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1569 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120082231-A Weather-resistant deformation-resistant heavy-duty anticorrosive coating system 深圳市希顺有机硅科技有限公司 2025-06-03 CN claimed
CN-120058769-A Preparation method for improving conversion rate of aromatic chlorosilane prepared by reduction of aromatic chlorosilane 江苏南大光电材料股份有限公司 2025-05-30 CN claimed
CN-120040771-A Hafnium hybridization carbon-rich polysiloxane flexible ablation material, preparation method and application thereof 四川大学 2025-05-27 CN claimed
CN-119613736-A Hydroxyl-terminated silicone oil containing fluorine and boron and preparation method thereof 沈阳化工大学 2025-03-14 CN claimed
CN-119463192-A Polysilazane containing perfluoro branched short chain and preparation method thereof 南京理工大学 2025-02-18 CN claimed
CN-119462154-A Large-specification graphite electrode special for metal silicon smelting and preparation method thereof 河北联晶炭素新材料科技有限公司 2025-02-18 CN claimed
CN-119041202-B Antibacterial finishing agent, application method thereof and antibacterial pure cotton towel 淄博新亚纺织有限公司 2025-01-07 CN claimed
CN-119264432-A Methyl phenyl high-boiling silicone oil and preparation method thereof 江西华昊化工有限公司 2025-01-07 CN claimed
CN-119041202-A Antibacterial finishing agent, application method thereof and antibacterial pure cotton towel 淄博新亚纺织有限公司 2024-11-29 CN claimed
CN-118909261-A SiCN precursor, ceramic matrix composite material for controlling deformation and preparation method 湖南天雅科技有限公司 2024-11-08 CN claimed
US-4992182-A Injection of aminopolycaroxylic acids or salts and organo-silicon compounds; chelation, stabilization of subterranean formations UNION OIL COMPANY OF CALIFORNIA (US) 1991-02-12 US claimed
US-4956486-A FORMING HYDROCARBON ADDUCTS FROM ORGANIC CHLORIDE IN THE PRESENCE OF LEWIS ACIDS DOW CORNING CORPORATION (US) 1990-09-11 US claimed
EP-0103824-B1 SEPARATION OF CHLOROSILANES DOW CORNING CORPORATION (US) 1989-01-25 EP claimed
US-4762938-A Process for the preparation of alkoxysilanes BAYER AKTIENGESELLSCHAFT (DE) 1988-08-09 US claimed
EP-0231497-A1 Silicone resist materials containing polysiloxanes KABUSHIKI KAISHA TOSHIBA (JP) 1987-08-12 EP claimed
US-4629801-A REDUCTION OF SILANE HALIDES WITH ALKALI OR ALKALINE EARTH METAL HYDRIDES USING SEQUESTERING CATALYST RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1986-12-16 US claimed
US-4560711-A Transparent organopolysiloxane compositions TORAY SILICONE COMPANY, LTD. (JP) 1985-12-24 US claimed
EP-0103824-A2 Separation of chlorosilanes DOW CORNING CORPORATION (US) 1984-03-28 EP claimed
US-4402796-A WITH SULFOLANE AND HYDROCARBONS COSOLVENTS DOW CORNING CORPORATION (US) 1983-09-06 US claimed
US-4033991-A REACTING HALOGENOSILANE WITH A METAL OXIME SHIN-ETSU CHEMICAL COMPANY, LIMITED (JA) 1977-07-05 US claimed