SCHEMBL1448087

SCHEMBL1448087

CCC[CH]N1CCCCCC1

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
POLB P06746 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1447629 1.00 ALDH1A1 (0.35) ALDH1A1L3MBTL1MEN1KMT2ATDP1
SCHEMBL378009 0.97
SCHEMBL1448045 0.92
SCHEMBL1447953 0.86
SCHEMBL2094342 0.85 L3MBTL1 (0.41) ALDH1A1L3MBTL1MEN1KMT2ATDP1
SCHEMBL6714009 0.83 L3MBTL1 (0.44) ALDH1A1L3MBTL1MEN1KMT2ATDP1
SCHEMBL4630231 0.82 TSHR (0.42) ALDH1A1L3MBTL1MEN1KMT2ATDP1
SCHEMBL6715588 0.81 TSHR (0.44) L3MBTL1MEN1KMT2ATDP1TSHR
SCHEMBL6722997 0.80 TSHR (0.42) ALDH1A1L3MBTL1MEN1KMT2ATDP1
SCHEMBL6716649 0.78 TSHR (0.46) L3MBTL1MEN1KMT2ATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3666757-A1 PROCESS FOR PREPARING A PIPERIDIN-4-ONE Karl-Franzens-Universität Graz (AT) 2020-06-17 EP disclosed
EP-2301627-A1 Novel antimalarial 3-azabicyclo[3.2.2]nonane derivatives University of Graz (AT) 2011-03-30 EP disclosed