Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29230355 | 1.00 | MEN1 (0.52) | MEN1KMT2ACYP2A6ALOX12NQO2 | |
| Ammonia Solution, Strong SCHEMBL793717 | 0.97 | MEN1 (0.50) | MEN1KMT2ACYP2A6ALOX12NQO2 | |
| SCHEMBL2929882 | 0.94 | MEN1 (0.48) | MEN1KMT2ACYP2A6ALOX12NQO2 | |
| SCHEMBL29807605 | 0.88 | TSHR (0.58) | MEN1KMT2ACYP2A6ALOX12NQO2 | |
| SCHEMBL599885 | 0.88 | TSHR (0.50) | MEN1KMT2ACYP2A6ALOX12NQO2 | |
| SCHEMBL322056 | 0.88 | TSHR (0.58) | MEN1KMT2ACYP2A6ALOX12NQO2 | |
| SCHEMBL4541419 | 0.83 | TSHR (0.52) | MEN1KMT2ACYP2A6ALOX12TSHR | |
| SCHEMBL7166999 | 0.83 | TSHR (0.46) | MEN1KMT2ACYP2A6ALOX12TSHR | |
| SCHEMBL19810100 | 0.83 | TSHR (0.52) | MEN1KMT2ACYP2A6ALOX12TSHR | |
| SCHEMBL5491066 | 0.83 | TSHR (0.52) | MEN1KMT2ACYP2A6ALOX12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422294-B2 | Cyclic compound, method for producing cyclic compound, and method for modifying biological molecule | JNC CORPORATION (JP) | 2016-08-23 | — | — | US | disclosed |
| US-20140364594-A1 | CYCLIC COMPOUND, METHOD FOR PRODUCING CYCLIC COMPOUND, AND METHOD FOR MODIFYING BIOLOGICAL MOLECULE | JNC CORP (JP) | 2014-12-11 | — | — | US | disclosed |
| US-8901312-B2 | Cyclic compound, method for producing cyclic compound, and method for modifying biological molecule | JNC CORPORATION (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20130011901-A1 | CYCLIC COMPOUND, METHOD FOR PRODUCING CYCLIC COMPOUND, AND METHOD FOR MODIFYING BIOLOGICAL MOLECULE | JNC CORPORATION (JP) | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364594-A1 | CYCLIC COMPOUND, METHOD FOR PRODUCING CYCLIC COMPOUND, AND METHOD FOR MODIFYING BIOLOGICAL MOLECULE | PTMS, CD38, TIMCC | MEN1 498/4885KMT2A 1404/4885CYP2A6 1637/4885 |
| US-20130011901-A1 | CYCLIC COMPOUND, METHOD FOR PRODUCING CYCLIC COMPOUND, AND METHOD FOR MODIFYING BIOLOGICAL MOLECULE | PTMS, CD38, TIMCC | MEN1 498/4885KMT2A 1404/4885CYP2A6 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.