SCHEMBL2929882

SCHEMBL2929882

c1ccc2cc3cc4cc5cc6cc7cc8cc9cc%10cc%11c(cc%10cc9cc8cc7cc6cc5cc4cc3cc2c1)CC%11

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALOX15 P16050 1/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
HBB P68871 1/20 0.46
HIF1A Q16665 1/20 0.46
GLA P06280 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
ACHE P22303 1/20 0.39
CYP2A6 P11509 5/20 0.39
ALOX12 P18054 1/20 0.39
NQO2 P16083 1/20 0.38
TSHR P16473 1/20 0.36
CYP1A2 P05177 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14482014 0.94 MEN1 (0.52) MEN1KMT2AALDH1A1CYP3A4HSD17B10
SCHEMBL29230355 0.94 MEN1 (0.52) MEN1KMT2AALDH1A1CYP3A4HSD17B10
Ammonia Solution, Strong SCHEMBL793717 0.91 MEN1 (0.50) MEN1KMT2AALDH1A1CYP3A4HSD17B10
SCHEMBL29750140 0.89 TSHR (0.52) MEN1KMT2AALDH1A1CYP3A4HSD17B10
SCHEMBL7166999 0.89 TSHR (0.46) MEN1KMT2AALDH1A1CYP3A4HSD17B10
SCHEMBL19810100 0.89 TSHR (0.52) MEN1KMT2AALDH1A1CYP3A4HSD17B10
SCHEMBL29750226 0.89 TSHR (0.52) MEN1KMT2AALDH1A1CYP3A4HSD17B10
SCHEMBL5491066 0.89 TSHR (0.52) MEN1KMT2AALDH1A1CYP3A4HSD17B10
SCHEMBL4541419 0.89 TSHR (0.52) MEN1KMT2AALDH1A1CYP3A4HSD17B10
SCHEMBL28311292 0.89 TSHR (0.52) MEN1KMT2AALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1971496-B1 LAMINATE OF THERMOPLASTIC POLYMER COMPOSITION HAVING LOW AIR PERMEABILITY AND PNEUMATIC TIRE USING SAME AS INNER LINER YOKOHAMA RUBBER CO LTD (JP) 2010-09-08 EP disclosed
US-20090038729-A1 LAMINATE OR THERMOPLASTIC POLYMER COMPOSITION HAVING LOW AIR PERMEABILITY AND PNEUMATIC TIRE USING SAME AS INNER LINER THE YOKOHAMA RUBBER CO., LTD (JP) 2009-02-12 US disclosed
EP-1971496-A1 LAMINATE OF THERMOPLASTIC POLYMER COMPOSITION HAVING LOW AIR PERMEABILITY AND PNEUMATIC TIRE USING SAME AS INNER LINER The Yokohama Rubber Co., Ltd. (JP) 2008-09-24 EP disclosed
WO-2007111584-A1 THERMOPLASTIC ELASTOMER COMPOSITION HAVING EXCELLENT LOW TEMPERATURE PROPERTY THE YOKOHAMA RUBBER CO., LTD. (JP) 2007-10-04 WO disclosed
WO-2007081323-A1 LAMINATE OF THERMOPLASTIC POLYMER COMPOSITION HAVING LOW AIR PERMEABILITY AND PNEUMATIC TIRE USING SAME AS INNER LINER THE YOKOHAMA RUBBER CO., LTD. (JP) 2007-07-19 WO disclosed