Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | FABP6 | P51161 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306994 | 0.79 | BACE1 (0.44) | BACE1KMT2AKCNH2HRH4HRH3 | |
| SCHEMBL9305009 | 0.79 | BACE1 (0.44) | BACE1KMT2AKCNH2HRH4HRH3 | |
| SCHEMBL15156916 | 0.77 | KCNH2 (0.46) | BACE1KCNH2HRH4HRH3KDM4E | |
| SCHEMBL31289470 | 0.74 | MEN1 (0.54) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL13122022 | 0.73 | CHRNB2 (0.46) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL21034172 | 0.73 | IDO1 (0.57) | BACE1HTR1DTLR9TLR8TLR7 | |
| SCHEMBL31289497 | 0.73 | MEN1 (0.52) | BACE1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL15156528 | 0.72 | SCN10A (0.40) | BACE1KCNH2HRH4HRH3HTR1D | |
| SCHEMBL15172692 | 0.72 | SCN10A (0.40) | BACE1KCNH2HRH4HRH3HTR1D | |
| SCHEMBL9620111 | 0.72 | TDP1 (0.45) | BACE1ALDH1A1MASP2MEN1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235575-B2 | Guanidine mimics as factor Xa inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2007-06-26 | — | — | US | disclosed |