Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MASP2 | O00187 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FABP6 | P51161 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619445 | 0.80 | TDP1 (0.46) | TDP1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL9620034 | 0.74 | TDP1 (0.44) | TDP1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL9619818 | 0.73 | TDP1 (0.53) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL10631855 | 0.72 | TDP1 (0.49) | TDP1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL14486917 | 0.72 | BACE1 (0.49) | TDP1ALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL8977446 | 0.71 | ALDH1A1 (0.44) | TDP1GAAALDH1A1KMT2AMAPT | |
| SCHEMBL13527924 | 0.71 | TDP1 (0.80) | TDP1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL9828402 | 0.71 | TDP1 (0.50) | TDP1GAAALDH1A1MAPTLMNA | |
| SCHEMBL10631932 | 0.70 | TDP1 (0.46) | TDP1GAAALDH1A1MEN1KMT2A | |
| SCHEMBL8252775 | 0.70 | TDP1 (0.67) | TDP1GAAALDH1A1MAPTBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |