Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12094827 | 0.68 | NAMPT (0.43) | ALDH1A1RAB9AMAPTGAALMNA | |
| SCHEMBL3462054 | 0.67 | CHRNB2 (0.33) | KMT2ACYP3A4 | |
| SCHEMBL25805454 | 0.67 | MAPK1 (0.38) | RAB9AGAAMAPK1L3MBTL1KMT2A | |
| SCHEMBL8284977 | 0.65 | MAPK1 (0.34) | GAAMAPK1 | |
| SCHEMBL28920780 | 0.64 | NPC1 (0.35) | ALDH1A1KDM4ERAB9ATDP1L3MBTL1 | |
| SCHEMBL25862835 | 0.64 | SMN1; SMN2 (0.35) | ALDH1A1KDM4ERAB9AMAPTL3MBTL1 | |
| SCHEMBL8916921 | 0.64 | PREP (0.36) | ALDH1A1TDP1MAPK1LMNAKMT2A | |
| SCHEMBL8654121 | 0.63 | MAPT (0.35) | MAPTMAPK1 | |
| SCHEMBL25457959 | 0.63 | APOBEC3A (0.46) | ALDH1A1KDM4ERAB9AMAPTMAPK1 | |
| SCHEMBL13576254 | 0.62 | HCAR3 (0.35) | GAAMAPK1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235575-B2 | Guanidine mimics as factor Xa inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2007-06-26 | — | — | US | disclosed |