Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 4/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18302407 | 0.80 | HTR3A (0.48) | TBK1IKBKEACHE | |
| SCHEMBL8358457 | 0.71 | NPC1 (0.45) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL17663437 | 0.71 | IP6K1 (0.51) | BACE1 | |
| SCHEMBL31432494 | 0.70 | ROCK1 (0.41) | — | |
| SCHEMBL17663434 | 0.70 | MAP4K4 (0.52) | BACE1 | |
| SCHEMBL1635678 | 0.69 | TBK1 (0.45) | TBK1IKBKEBACE1PRMT5WDR77 | |
| SCHEMBL14486911 | 0.69 | JAK2 (0.50) | BACE1PRMT5WDR77HTR1D | |
| SCHEMBL1943238 | 0.68 | IDO1 (0.50) | TBK1BACE1NPC1ALDH1A1RAB9A | |
| SCHEMBL7214975 | 0.68 | IDO1 (0.36) | IKBKE | |
| SCHEMBL18683348 | 0.68 | IDO1 (0.50) | IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235575-B2 | Guanidine mimics as factor Xa inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2007-06-26 | — | — | US | disclosed |
| US-7235575-B2 | Guanidine mimics as factor Xa inhibitors | BRISTOL MYERS SQUIBB COMPANY (US) | 2007-06-26 | — | — | US | disclosed |