Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140567 | 1.00 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL29520458 | 0.81 | GAA (0.53) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL3718043 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL3714585 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL12979662 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL715038 | 0.80 | ALDH1A1 (0.50) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL2380656 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL8902371 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL19316681 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL12937998 | 0.79 | MAOB (0.44) | SMN1; SMN2ALDH1A1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235580-B2 | Mitotic kinesin inhibitors | MERCK & CO., INC. (US) | 2007-06-26 | — | — | US | disclosed |