Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12979662 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL19316681 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL14227654 | 0.83 | — | — | |
| SCHEMBL715038 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL3718043 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL3714585 | 0.82 | ALDH1A1 (0.50) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL8902371 | 0.82 | SMN1; SMN2 (0.42) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL17393083 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL25405355 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2PKMALDH1A1KMT2AMAPT | |
| SCHEMBL14487477 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2PKMALDH1A1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116333317-A | POSS-based hydrophobic material and preparation method thereof | 安徽中烟工业有限责任公司 | 2023-06-27 | — | — | CN | claimed |
| US-10465096-B2 | Metal chemical mechanical planarization (CMP) composition and methods therefore | VERSUM MATERIALS US, LLC (US) | 2019-11-05 | — | — | US | claimed |
| WO-1995017755-A1 | PROCESS FOR PRODUCING AN INSULATION SYSTEM | ABB PATENT GMBH (DE) | 1995-06-29 | — | — | WO | claimed |
| WO-2023278686-A1 | SPIROCYCLIC PYRIDINE-1,5-DIONES EXHIBITING MNK INHIBITION AND THEIR METHOD OF USE | 4E THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| CN-106336739-B | Colorant dispersion for color filter, coloring composition for color filter, and display device | DNP精细化工股份有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-112646538-A | Novel UV thermal dual-curing adhesive and preparation method thereof | 深圳市宏进科技有限公司 | 2021-04-13 | — | — | CN | disclosed |
| EP-2897625-A2 | AMNIOTIC MEMBRANE AND ITS USE IN WOUND HEALING AND TISSUE ENGINEERING CONSTRUCTS | Wake Forest University Health Sciences (US) | 2015-07-29 | — | — | EP | disclosed |
| WO-2014040026-A2 | AMNIOTIC MEMBRANE AND ITS USE IN WOUND HEALING AND TISSUE ENGINEERING CONSTRUCTS | WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) | 2014-03-13 | — | — | WO | disclosed |
| WO-2011127350-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-10-13 | — | — | WO | disclosed |
| US-8017776-B2 | Methods for synthesis of acyloxyalkyl compounds | XENOPORT, INC. (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100041882-A1 | METHODS FOR SYNTHESIS OF ACYLOXYALKYL COMPOUNDS | XENOPORT, INC. (US) | 2010-02-18 | — | — | US | disclosed |
| US-7662987-B2 | Oxidation of 1-acyl alkyl compound under anhydrous condition | XENOPORT, INC. (US) | 2010-02-16 | — | — | US | disclosed |
| US-7235580-B2 | Mitotic kinesin inhibitors | MERCK & CO., INC. (US) | 2007-06-26 | — | — | US | disclosed |
| US-20050070715-A1 | Methods for synthesis of acyloxyalkyl compounds | ARBOR PHARMACEUTICALS, LLC | 2005-03-31 | — | — | US | disclosed |
| WO-2005010011-A2 | METHODS OF SYNTHESIS OF ACYLOXYALKYL COMPOUNDS | XENOPORT, INC. (US) | 2005-02-03 | — | — | WO | disclosed |
| EP-1263753-A1 | IMIDAZOL DERIVATIVES AS RAF KINASE INHIBITORS | SmithKline Beecham plc (GB) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001066539-A1 | IMIDAZOL DERIVATIVES AS RAF KINASE INHIBITORS | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-09-13 | — | — | WO | disclosed |
| US-5705009-A | Process for producing an insulation system | ABB PATENT GMBH (DE) | 1998-01-06 | — | — | US | disclosed |
| WO-1995017755-A1 | PROCESS FOR PRODUCING AN INSULATION SYSTEM | ABB PATENT GMBH (DE) | 1995-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070715-A1 | Methods for synthesis of acyloxyalkyl compounds | AADAC, CYP2D6, CYP3A7 | SMN1; SMN2 3880/4885PKM 2057/4885ALDH1A1 103/4885 |
| US-20100041882-A1 | METHODS FOR SYNTHESIS OF ACYLOXYALKYL COMPOUNDS | AADAC, CYP2D6, CYP3A7 | SMN1; SMN2 3880/4885PKM 2057/4885ALDH1A1 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.