SCHEMBL1448786

SCHEMBL1448786

C=Cc1ccc(C([SiH3])(OC)OC)cc1

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
TRPA1 O75762 1/20 0.36
TSHR P16473 1/20 0.36
HDAC8 Q9BY41 1/20 0.35
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2155732 0.79 ALDH1A1 (0.41) ALDH1A1TRPA1TSHRHDAC8TAS1R3
SCHEMBL2556558 0.77 ALDH1A1 (0.48) ALDH1A1TRPA1TSHRHDAC8TAS1R3
SCHEMBL29088811 0.75 ALDH1A1 (0.41) ALDH1A1TRPA1TSHRHDAC8TAS1R3
Methoxymethane SCHEMBL28668345 0.74 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8
Methoxymethane SCHEMBL28929715 0.72 ALDH1A1 (0.48) ALDH1A1HDAC8CHRNB2CHRNB4CHRNA3
SCHEMBL5200151 0.72 ALDH1A1 (0.48) ALDH1A1TRPA1TSHRHDAC8TAS1R3
Ethylene SCHEMBL12098523 0.71 MAPK1 (0.41) ALDH1A1TSHR
SCHEMBL10350131 0.71 ALDH1A1 (0.43) ALDH1A1TSHRTDP1
SCHEMBL6682418 0.71 ALDH1A1 (0.46) ALDH1A1TRPA1TSHRHDAC8TAS1R3
SCHEMBL3898714 0.70 MAPK1 (0.44) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4545602-A1 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Mitsubishi Chemical Corporation (JP) 2025-04-30 EP disclosed
EP-4502080-A2 RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Mitsubishi Chemical Corporation (JP) 2025-02-05 EP disclosed
US-20250011596-A1 SILICONE CORE ACRYLIC SHELL IMPACT MODIFIERS CONTAINING PHOSPHORUS ROHM & HAAS (US) 2025-01-09 US disclosed
EP-4444774-A1 SILICONE CORE ACRYLIC SHELL IMPACT MODIFIERS CONTAINING PHOSPHORUS Rohm and Haas Company (US) 2024-10-16 EP disclosed
US-12030973-B2 Thermoplastic resin composition and molded article of same TECHNO-UMG CO., LTD. (JP) 2024-07-09 US disclosed
CN-118302464-A Phosphorus-containing silicone core acrylic shell impact modifiers 罗门哈斯公司 2024-07-05 CN disclosed
US-11976189-B2 Thermoplastic resin composition and molded article TECHNO-UMG CO., LTD. (JP) 2024-05-07 US disclosed
US-20240092961-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE OF SAME TECHNO-UMG CO., LTD. (JP) 2024-03-21 US disclosed
US-20240043678-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE TECHNO-UMG CO., LTD. (JP) 2024-02-08 US disclosed
EP-4317309-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Techno-UMG Co., Ltd. (JP) 2024-02-07 EP disclosed
EP-0806440-A2 Composite rubber particles and graft copolymer particles of composite rubber Kaneka Corporation (JP) 1997-11-12 EP disclosed
EP-0791617-A1 PARTICULATE SILICONE-MODIFIED ACRYLIC RUBBER, PARTICULATE GRAFT COPOLYMER BASED ON SILICONE-MODIFIED ACRYLIC RUBBER, AND THERMOPLASTIC RESIN COMPOSITION KANEKA CORPORATION (JP) 1997-08-27 EP disclosed
EP-0584363-B1 GRAFT COPOLYMER PARTICLE, PRODUCTION THEREOF, AND COMPOSITION THEREOF MITSUBISHI RAYON CO (JP) 1997-06-11 EP disclosed
EP-0502480-B1 Thermoplastic resin compositions MITSUBISHI RAYON CO (JP) 1996-08-14 EP disclosed
US-5543460-A GRAFT POLYMERIZING VINYL MONOMER ONTO RUBBER MITSUBISHI RAYON CO., LTD. (JP) 1996-08-06 US disclosed
EP-0523251-B1 THERMOPLASTIC RESIN COMPOSITION MITSUBISHI RAYON CO (JP) 1996-07-24 EP disclosed
US-5322881-A Consisting of polyamides, polymethacrylimides, polyether-imides amd polysiloxane graft resins MITSUBISHI RAYON CO., LTD. (JP) 1994-06-21 US disclosed
EP-0584363-A1 GRAFT COPOLYMER PARTICLE, PRODUCTION THEREOF, AND COMPOSITION THEREOF MITSUBISHI RAYON CO., LTD. (JP) 1994-03-02 EP disclosed
EP-0523251-A1 THERMOPLASTIC RESIN COMPOSITION MITSUBISHI RAYON CO., LTD. (JP) 1993-01-20 EP disclosed
EP-0502480-A2 Thermoplastic resin compositions MITSUBISHI RAYON CO., LTD. (JP) 1992-09-09 EP disclosed