SCHEMBL2556558

SCHEMBL2556558

C=Cc1ccc(C(C)(C)OC)cc1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
TRPA1 O75762 1/20 0.37
TSHR P16473 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
HSD11B1 P28845 1/20 0.33
MAPK1 P28482 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
CYP2A6 P11509 1/20 0.31
ALOX15 P16050 1/20 0.31
RORC P51449 1/20 0.31
CYP1A2 P05177 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6682418 0.81 ALDH1A1 (0.46) ALDH1A1TRPA1TSHRHDAC8TAS1R3
SCHEMBL43313 0.81 MAPK1 (0.46) ALDH1A1TSHRTDP1HSD11B1MAPK1
Methoxymethane SCHEMBL28668345 0.80 ALDH1A1 (0.50) ALDH1A1TRPA1TSHRHDAC8MAPK1
SCHEMBL9173511 0.80 ALDH1A1 (0.52) ALDH1A1TSHRTDP1CYP2A6
SCHEMBL5270257 0.79 ALDH1A1 (0.44) ALDH1A1TRPA1TSHRHDAC8TDP1
SCHEMBL10245980 0.78 ALDH1A1 (0.42) ALDH1A1TRPA1TSHRHDAC8TAS1R3
SCHEMBL5274018 0.78 ALDH1A1 (0.42) ALDH1A1TRPA1TSHRHDAC8TAS1R3
SCHEMBL1448786 0.77 ALDH1A1 (0.46) ALDH1A1TRPA1TSHRHDAC8TAS1R3
SCHEMBL1024017 0.77 ALDH1A1 (0.58) ALDH1A1TRPA1TSHRHDAC8TAS1R3
SCHEMBL15198 0.77 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TDP1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748530-B2 Arborescent polymers and process for making same THE UNIVERSITY OF AKRON (US) 2014-06-10 US claimed
US-20130303688-A1 ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME LANXESS INC (CA) 2013-11-14 US claimed
US-20130261250-A1 ARBORESCENT POLYMERS HAVING A CORE WITH A HIGH GLASS TRANSITION TEMPERATURE AND PROCESS FOR MAKING SAME LANXESS INC. (CA) 2013-10-03 US claimed
US-20130144021-A1 ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME LANXESS, INC. (CA) 2013-06-06 US claimed
EP-2558509-A1 ARBORESCENT POLYMERS HAVING A CORE WITH A HIGH GLASS TRANSITION TEMPERATURE AND PROCESS FOR MAKING SAME Lanxess Inc. (CA) 2013-02-20 EP claimed
US-8258230-B2 Arborescent polymers and process for making same THE UNIVERSITY OF AKRON (US) 2012-09-04 US claimed
US-20110301281-A1 ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME LANXESS, INC. (CA) 2011-12-08 US claimed
WO-2011127562-A1 ARBORESCENT POLYMERS HAVING A CORE WITH A HIGH GLASS TRANSITION TEMPERATURE AND PROCESS FOR MAKING SAME LANXESS INC. (CA) 2011-10-20 WO claimed
US-20100267884-A1 ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME LANXESS, INC. (CA) 2010-10-21 US claimed
US-20100249316-A1 ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME THE UNIVERSITY OF AKRON (US) 2010-09-30 US claimed
US-20100063211-A1 ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME LANXESS, INC. (CA) 2010-03-11 US claimed
EP-2064247-A2 ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME THE UNIVERSITY OF AKRON (US) 2009-06-03 EP claimed
WO-2008027589-A2 ARBORESCENT POLYMERS AND PROCESS FOR MAKING SAME THE UNIVERSITY OF AKRON (US) 2008-03-06 WO claimed
CN-109867741-A Novel fire resistant polyisobutene base thermoplastic elastomer and preparation method thereof 大连理工大学 2019-06-11 CN disclosed
CN-102432757-B Copolymers of conjugated triene for improved filler interactions GOODYEAR TIRE & RUBBER 2015-07-22 CN disclosed
US-8748530-B2 Arborescent polymers and process for making same THE UNIVERSITY OF AKRON (US) 2014-06-10 US disclosed
EP-1219649-A1 PROCESS FOR PRODUCING FUNCTIONAL STYRENE COPOLYMER AND FUNCTIONAL STYRENE COPOLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-07-03 EP disclosed
US-5214105-A Preparation of graft copolymers from macromolecules containing reactive tertiary structures UNIVERSITY OF OTTAWA (CA) 1993-05-25 US disclosed
US-5210148-A Styrenic polymer containing polyisobutylene side-chains UNIVERSITY OF OTTAWA (CA) 1993-05-11 US disclosed
US-5084522-A Styrenic polymer containing pendant reactive tertiary structures and the preparation thereof UNIVERSITY OF OTTAWA (CA) 1992-01-28 US disclosed