Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14556062 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1LMNAGAAKMT2A | |
| SCHEMBL509207 | 0.80 | PDE4D (0.56) | HSD17B10KDM4EALDH1A1HPGDCA12 | |
| SCHEMBL14556069 | 0.78 | KDM4E (0.51) | HSD17B10KDM4EALDH1A1HPGDCA12 | |
| SCHEMBL14556107 | 0.75 | MAPK1 (0.44) | HSD17B10KDM4EALDH1A1HPGDCA12 | |
| SCHEMBL23028359 | 0.74 | MEN1 (0.36) | KDM4EMAPK1SMN1; SMN2TSHRLMNA | |
| SCHEMBL25664507 | 0.71 | GAA (0.57) | HSD17B10KDM4EALDH1A1CA12CA1 | |
| SCHEMBL14488430 | 0.69 | KDM4E (0.41) | KDM4EALDH1A1MAPK1SMN1; SMN2TSHR | |
| SCHEMBL13448513 | 0.69 | LMNA (0.35) | HSD17B10KDM4EMAPK1SMN1; SMN2LMNA | |
| SCHEMBL18770421 | 0.69 | MAPK1 (0.48) | HSD17B10KDM4EALDH1A1HPGDCA12 | |
| SCHEMBL874634 | 0.69 | LMNA (0.55) | HSD17B10KDM4EALDH1A1HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006792-A1 | ANTIVIRAL COMPOUNDS | PHARMARESOURCES (SHANGHAI) CO., LTD. (CN) | 2013-01-10 | — | — | WO | disclosed |
| WO-2013006792-A1 | ANTIVIRAL COMPOUNDS | PHARMARESOURCES (SHANGHAI) CO., LTD. (CN) | 2013-01-10 | — | — | WO | disclosed |