SCHEMBL874634

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22950631	0.78	LMNA (0.57)	LMNARAB9AHSD17B10CA12CA1
	SCHEMBL873891	0.78	LMNA (0.57)	LMNARAB9AHSD17B10CA12CA1
	SCHEMBL17050149	0.75	LMNA (0.55)	LMNARAB9AHSD17B10CA12CA1
	SCHEMBL21217825	0.72	RAB9A (0.36)	RAB9ASMN1; SMN2ALDH1A1
	SCHEMBL4789370	0.70	LMNA (0.78)	LMNARAB9AHSD17B10SMN1; SMN2HPGD
	SCHEMBL16153996	0.69	RAB9A (1.00)	LMNARAB9AHSD17B10SMN1; SMN2ALDH1A1
	SCHEMBL14487995	0.69	HSD17B10 (0.49)	LMNARAB9AHSD17B10CA12CA1
	SCHEMBL14556107	0.69	MAPK1 (0.44)	LMNARAB9AHSD17B10CA12CA1
	SCHEMBL17653859	0.69	SMN1; SMN2 (0.40)	LMNAHSD17B10CA12CA1CA2
	SCHEMBL443306	0.67	CA12 (0.56)	LMNARAB9AHSD17B10CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.