Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 13/20 | 0.58 |
| ▸ | MAPT | P10636 | 12/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17668340 | 0.97 | LMNA (0.59) | LMNAMAPTRECQLPOLBTP53 | |
| SCHEMBL15613050 | 0.92 | MAPT (0.61) | LMNAMAPTRECQLPOLBTP53 | |
| SCHEMBL17465684 | 0.86 | LMNA (0.60) | LMNAMAPTRECQLPOLBTP53 | |
| SCHEMBL17465683 | 0.86 | MAPT (0.60) | LMNAMAPTRECQLPOLBTP53 | |
| Hydrochloric Acid SCHEMBL15847781 | 0.85 | LMNA (0.59) | LMNAMAPTRECQLPOLBTP53 | |
| Hydrochloric Acid SCHEMBL15847850 | 0.85 | MAPT (0.59) | LMNAMAPTRECQLPOLBTP53 | |
| SCHEMBL15847613 | 0.84 | LMNA (0.58) | LMNAMAPTRECQLPOLBTP53 | |
| SCHEMBL15848305 | 0.83 | MAPT (0.53) | LMNAMAPTRECQLPOLBTP53 | |
| SCHEMBL20033697 | 0.82 | LMNA (0.66) | LMNAMAPTRECQLPOLBTP53 | |
| SCHEMBL19332177 | 0.82 | POLB (0.60) | LMNAMAPTRECQLPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2726459-A1 | SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | Institute for Hepatitis and Virus Research (US) | 2014-05-07 | — | — | EP | claimed |
| WO-2013006394-A1 | SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | INSTITUTE FOR HEPATITIS AND VIRUS RESEARCH (US) | 2013-01-10 | — | — | WO | claimed |