Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 11/20 | 0.66 |
| ▸ | MAPT | P10636 | 10/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 10/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15613050 | 0.90 | MAPT (0.61) | LMNAMAPTRECQLTP53MEN1 | |
| SCHEMBL15847362 | 0.83 | MAPT (0.56) | LMNAMAPTRECQLTP53KMT2A | |
| SCHEMBL15847785 | 0.83 | MAPT (0.61) | LMNAMAPTRECQLTP53MEN1 | |
| SCHEMBL17668340 | 0.83 | LMNA (0.59) | LMNAMAPTRECQLTP53MEN1 | |
| SCHEMBL15847595 | 0.83 | KMT2A (0.63) | LMNAMAPTRECQLTP53KMT2A | |
| SCHEMBL15847593 | 0.83 | KMT2A (0.63) | LMNAMAPTRECQLTP53KMT2A | |
| SCHEMBL15848010 | 0.83 | KMT2A (0.63) | LMNAMAPTRECQLTP53KMT2A | |
| SCHEMBL14484956 | 0.83 | MAPT (0.70) | LMNAMAPTRECQLTP53MEN1 | |
| SCHEMBL14488016 | 0.82 | LMNA (0.58) | LMNAMAPTRECQLTP53MEN1 | |
| SCHEMBL17465703 | 0.82 | KMT2A (0.59) | LMNAMAPTRECQLTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9938236-B2 | Antiviral agents against HBV infection | DREXEL UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |