Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | XBP1 | P17861 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26463794 | 0.82 | CYP19A1 (0.78) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15045213 | 0.81 | KMT2A (0.71) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11752812 | 0.81 | VCAM1 (0.60) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3701951 | 0.80 | CA12 (0.71) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15045384 | 0.79 | KMT2A (0.60) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL27181624 | 0.79 | MAPT (0.80) | MAPTLMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL30292407 | 0.79 | MAPT (0.54) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL28577784 | 0.78 | CYP19A1 (0.71) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL23057261 | 0.77 | IDO1 (0.72) | MAPTLMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29561931 | 0.77 | MEN1 (0.62) | MAPTLMNAALDH1A1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2726459-A1 | SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | Institute for Hepatitis and Virus Research (US) | 2014-05-07 | — | — | EP | claimed |
| WO-2013006394-A1 | SULFAMOYLBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION | INSTITUTE FOR HEPATITIS AND VIRUS RESEARCH (US) | 2013-01-10 | — | — | WO | claimed |