Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | PGR | P06401 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.54 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CDK7 | P50613 | 1/20 | 0.54 |
| ▸ | CCNH | P51946 | 1/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19157169 | 0.87 | MEN1 (0.61) | KMT2APGRMEN1MAPTALDH1A1 | |
| SCHEMBL12112924 | 0.86 | IDH1 (0.58) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL22455328 | 0.84 | PGR (0.72) | KMT2APGRMEN1MAPTALDH1A1 | |
| SCHEMBL15045213 | 0.84 | KMT2A (0.71) | KMT2APGRMEN1MAPTALDH1A1 | |
| SCHEMBL22455347 | 0.84 | MAPT (0.60) | KMT2APGRMEN1MAPTALDH1A1 | |
| SCHEMBL7571133 | 0.83 | MAPT (0.63) | KMT2APGRMEN1MAPTALDH1A1 | |
| SCHEMBL5163794 | 0.82 | LMNA (0.62) | KMT2APGRMEN1MAPTALDH1A1 | |
| SCHEMBL21693592 | 0.82 | KMT2A (0.73) | KMT2APGRMEN1MAPTALDH1A1 | |
| SCHEMBL10361762 | 0.82 | MAPT (0.65) | KMT2APGRMEN1MAPTALDH1A1 | |
| SCHEMBL12112914 | 0.81 | MEN1 (0.60) | KMT2APGRMEN1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166553-A1 | ANTIMETASTATIC COMPOUNDS | UNIV BRIGHAM YOUNG (US) | 2016-06-16 | — | — | US | disclosed |
| US-20130158035-A1 | ANTIMETASTATIC COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158035-A1 | ANTIMETASTATIC COMPOUNDS | MET, HGFAC, HGF | KMT2A 3928/4885PGR 848/4885MEN1 391/4885 |
| US-20160166553-A1 | ANTIMETASTATIC COMPOUNDS | MET, HGFAC, HGF | KMT2A 3928/4885PGR 848/4885MEN1 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.