Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740844 | 1.00 | NFE2L2 (0.52) | NFE2L2HCAR2KEAP1TTRAPP | |
| SCHEMBL9740851 | 1.00 | NFE2L2 (0.52) | NFE2L2HCAR2KEAP1TTRAPP | |
| SCHEMBL5911481 | 0.85 | HCAR2 (0.46) | NFE2L2HCAR2KEAP1CA12CA1 | |
| SCHEMBL5911478 | 0.85 | HCAR2 (0.46) | NFE2L2HCAR2KEAP1CA12CA1 | |
| SCHEMBL6120505 | 0.80 | HDAC6 (0.35) | CYP2C9CYP2C19 | |
| SCHEMBL15630729 | 0.80 | HDAC6 (0.35) | CYP2C9CYP2C19 | |
| SCHEMBL1716949 | 0.80 | HCAR2 (0.50) | NFE2L2HCAR2KEAP1TTRAPP | |
| SCHEMBL1716947 | 0.80 | HCAR2 (0.50) | NFE2L2HCAR2KEAP1TTRAPP | |
| SCHEMBL8459343 | 0.78 | HCAR2 (0.52) | HCAR2TTRCA12CA1CA2 | |
| SCHEMBL13433290 | 0.78 | HCAR2 (0.48) | NFE2L2HCAR2KEAP1TTRAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7226661-B2 | Synthesis of quinones and phenols on solid support | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-06-05 | — | — | US | disclosed |