Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459344 | 1.00 | HCAR2 (0.52) | HCAR2MAPTALDH1A1TTRDPP4 | |
| SCHEMBL22734091 | 0.84 | MAPT (0.49) | HCAR2MAPTALDH1A1TTRDPP4 | |
| SCHEMBL11702437 | 0.83 | NPSR1 (0.43) | HCAR2MAPTALDH1A1TTRDPP4 | |
| SCHEMBL11702432 | 0.83 | NPSR1 (0.43) | HCAR2MAPTALDH1A1TTRDPP4 | |
| Hydrochloric Acid SCHEMBL29911009 | 0.82 | MAPT (0.47) | HCAR2MAPTALDH1A1TTRDPP4 | |
| SCHEMBL8152585 | 0.82 | MAPT (0.50) | HCAR2MAPTALDH1A1TTRDPP4 | |
| SCHEMBL5643847 | 0.82 | MAPT (0.50) | HCAR2MAPTALDH1A1TTRDPP4 | |
| SCHEMBL7021082 | 0.80 | MAPT (0.49) | HCAR2MAPTALDH1A1TTRDPP4 | |
| SCHEMBL12710484 | 0.80 | MAPT (0.58) | HCAR2MAPTALDH1A1TTRDPP4 | |
| SCHEMBL7701708 | 0.80 | MAPT (0.45) | HCAR2MAPTALDH1A1TTRDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107778-A1 | NOVEL PROTEASE INHIBITORS FOR TREATMENT OF CORONAVIRUS INFECTIONS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-05-23 | — | — | WO | disclosed |
| US-20230265057-A1 | INHIBITORS OF PARG | ARASE THERAPEUTICS INC. | 2023-08-24 | — | — | US | disclosed |
| US-11040028-B2 | Penicinotam derivative, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2021-06-22 | — | — | US | disclosed |
| US-10040806-B2 | Microbiocidally active benzoxaboroles | SYNGENTA PARTICIPATIONS AG (CH) | 2018-08-07 | — | — | US | disclosed |
| US-20160347773-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-12-01 | — | — | US | disclosed |
| US-7868205-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| US-7868205-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2011-01-11 | — | — | US | disclosed |
| US-20080132459-A1 | Inhibitors of Histone Deacetylase | METHYLGENE, INC. (CA) | 2008-06-05 | — | — | US | disclosed |
| US-20080132459-A1 | Inhibitors of Histone Deacetylase | METHYLGENE, INC. (CA) | 2008-06-05 | — | — | US | disclosed |
| US-5962002-A | 1,1,4,4-SUBSTITUTED DIHYDRONAPHTHALENE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1999-10-05 | — | — | US | disclosed |
| EP-0802730-B1 | PESTICIDAL COMPOUNDS | BTG INT LTD (GB) | 1999-06-23 | — | — | EP | disclosed |
| EP-0802730-A1 | PESTICIDAL COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021355-A1 | PESTICIDAL COMPOUNDS | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132459-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC5, HDAC3 | HCAR2 1635/4885MAPT 2110/4885ALDH1A1 796/4885 |
| US-20230265057-A1 | INHIBITORS OF PARG | PARG, PARN, PLG | HCAR2 1746/4885MAPT 4237/4885ALDH1A1 3863/4885 |
| US-20160347773-A1 | MICROBIOCIDALLY ACTIVE BENZOXABOROLES | MPO, BROX, MANBA | HCAR2 1447/4885MAPT 3740/4885ALDH1A1 1549/4885 |
| US-11040028-B2 | Penicinotam derivative, preparation method and use thereof | TPMT, MAPT, TLR4 | HCAR2 2326/4885MAPT 2/4885ALDH1A1 1738/4885 |
| US-10040806-B2 | Microbiocidally active benzoxaboroles | MPO, BROX, MANBA | HCAR2 1447/4885MAPT 3740/4885ALDH1A1 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.