Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | CCR9 | P51686 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CDC42 | P60953 | 1/20 | 0.39 |
| ▸ | RAC1 | P63000 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1395988 | 0.87 | AKR1C3 (0.43) | KDM4EALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL8756075 | 0.87 | CNR2 (0.45) | KDM4EALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL1395986 | 0.87 | AKR1C3 (0.43) | KDM4EALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL220266 | 0.84 | AKR1C3 (0.47) | KDM4EALDH1A1CYP1A2HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL220256 | 0.82 | AKR1C3 (0.44) | KDM4EALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL1396028 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL27816060 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL28917251 | 0.81 | CYP1A2 (0.42) | KDM4EALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL506525 | 0.81 | AKR1C3 (0.49) | KDM4EALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL220299 | 0.81 | AKR1C3 (0.43) | KDM4EALDH1A1CYP1A2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110054020-A1 | NAPTHYLENE INHIBITORS OF CYCLOOXYGENASE | AUSPEX PHARMACEUTICALS, INC. (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054020-A1 | NAPTHYLENE INHIBITORS OF CYCLOOXYGENASE | PTGES, PTGES2, PTGES3 | KDM4E 772/4885ALDH1A1 305/4885CYP1A2 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.