Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | CDC42 | P60953 | 1/20 | 0.44 |
| ▸ | RAC1 | P63000 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | CCR9 | P51686 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11117316 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HSD17B10NPC1LMNAMAPT | |
| SCHEMBL220266 | 0.85 | AKR1C3 (0.47) | AKR1C3AKR1C2PTGS1KDM4EAKR1C1 | |
| SCHEMBL9333964 | 0.84 | AKR1C3 (0.43) | AKR1C3AKR1C2PTGS1KDM4EAKR1C1 | |
| SCHEMBL8756075 | 0.84 | CNR2 (0.45) | AKR1C3AKR1C2PTGS1KDM4EAKR1C1 | |
| SCHEMBL9333423 | 0.84 | AKR1C3 (0.43) | AKR1C3AKR1C2PTGS1KDM4EAKR1C1 | |
| Hydrochloric Acid SCHEMBL220256 | 0.83 | AKR1C3 (0.44) | AKR1C3AKR1C2PTGS1KDM4EAKR1C1 | |
| SCHEMBL220210 | 0.83 | AKR1C3 (0.44) | AKR1C3AKR1C2PTGS1KDM4EAKR1C1 | |
| SCHEMBL9330830 | 0.83 | AKR1C3 (0.42) | AKR1C3AKR1C2PTGS1KDM4EAKR1C1 | |
| SCHEMBL28917251 | 0.83 | CYP1A2 (0.42) | AKR1C3AKR1C2PTGS1KDM4EAKR1C1 | |
| SCHEMBL9330626 | 0.83 | AKR1C3 (0.42) | AKR1C3AKR1C2PTGS1KDM4EAKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975432-A | Process for preparing 2-(6-methoxy-2-naphthyl)propionic acid | SYNTEX CORPORATION (PM) | 1976-08-17 | — | — | US | claimed |
| US-20150183737-A1 | COMPOSITIONS AND METHODS FOR SUBSTRATE-SELECTIVE INHIBITION OF ENDOCANNABINOID OXYGENATION | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2015-07-02 | — | — | US | disclosed |
| US-20120029226-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | DSM IP ASSETS B.V. (NL) | 2012-02-02 | — | — | US | disclosed |
| EP-0687735-B1 | Method for enzymatic transesterification | SUEDDEUTSCHE KALKSTICKSTOFF (DE) | 1997-05-07 | — | — | EP | disclosed |
| EP-0687735-A1 | Method for enzymatic transesterification | SKW Trostberg Aktiengesellschaft (DE) | 1995-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150183737-A1 | COMPOSITIONS AND METHODS FOR SUBSTRATE-SELECTIVE INHIBITION OF ENDOCANNABINOID OXYGENATION | CNR2, FAAH2, FAAH | AKR1C3 729/4885AKR1C2 821/4885PTGS1 24/4885 |
| US-20120029226-A1 | METHOD FOR THE SYNTHESIS OF CHIRAL ALPHA-ARYL PROPIONIC ACID DERIVATIVES | GRIA1, GRIA3, GRIA2 | AKR1C3 233/4885AKR1C2 273/4885PTGS1 1036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.