Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14488958 | 0.99 | THRB (0.59) | THRBTHRA | |
| SCHEMBL14488974 | 0.97 | THRB (0.61) | THRBTHRA | |
| SCHEMBL14488972 | 0.97 | THRB (0.57) | THRBTHRA | |
| SCHEMBL14489387 | 0.91 | THRB (0.69) | THRBTHRA | |
| SCHEMBL14488981 | 0.91 | THRB (0.61) | THRBTHRA | |
| SCHEMBL14489101 | 0.90 | THRB (0.70) | THRBTHRA | |
| SCHEMBL14488997 | 0.90 | THRB (0.61) | THRBTHRA | |
| SCHEMBL14489068 | 0.88 | THRB (0.72) | THRBTHRA | |
| SCHEMBL14488837 | 0.88 | THRB (0.61) | THRBTHRA | |
| SCHEMBL14489076 | 0.87 | THRB (0.68) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230031-B2 | Thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-06-12 | — | — | US | disclosed |