SCHEMBL14488991

SCHEMBL14488991

Cc1nc(N)nc(N(C)c2ccc3c(O)c(/N=N\c4ccc5c(S(=O)(=O)O)cccc5c4S(=O)(=O)O)c(SOOO)cc3c2)n1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PHLPP2 Q6ZVD8 2/20 0.37
▸ PTPN11 Q06124 1/20 0.34
▸ ENPP2 Q13822 3/20 0.34
▸ ATIC P31939 2/20 0.34
▸ SUMO2 P61956 1/20 0.34
▸ SUMO1 P63165 1/20 0.34
▸ SENP7 Q9BQF6 1/20 0.34
▸ SENP2 Q9HC62 1/20 0.34
▸ MEN1 O00255 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ THRB P10828 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ CYP1A2 P05177 3/20 0.33
▸ MPL P40238 1/20 0.32
▸ CTRC Q99895 1/20 0.32
▸ CTRB1 P17538 1/20 0.30
▸ ALDH1A1 P00352 3/20 0.30
▸ HIF1A Q16665 2/20 0.30
▸ NSD2 O96028 1/20 0.30
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14355349 0.82 ALDH1A1 (0.42) PHLPP2PTPN11ENPP2ATICSUMO2
SCHEMBL3698750 0.81 PHLPP2 (0.42) PHLPP2ENPP2ATICSUMO2SUMO1
SCHEMBL29575167 0.81 PHLPP2 (0.42) PHLPP2ENPP2ATICSUMO2SUMO1
SCHEMBL3698744 0.81 PHLPP2 (0.42) PHLPP2ENPP2ATICSUMO2SUMO1
SCHEMBL13387399 0.77 PRMT1 (0.42) PHLPP2PTPN11ENPP2MEN1KMT2A
SCHEMBL13860805 0.77 ENPP2 (0.44) PHLPP2PTPN11ENPP2MEN1KMT2A
SCHEMBL10024206 0.76 MEN1 (0.42) PHLPP2ENPP2ATICMEN1KMT2A
SCHEMBL13292121 0.75 ENPP2 (0.53) PHLPP2PTPN11ENPP2ATICSUMO2
SCHEMBL13387299 0.74 FUT8 (0.43) PHLPP2PTPN11ENPP2MEN1KMT2A
SCHEMBL14488862 0.73 MEN1 (0.37) PHLPP2PTPN11ENPP2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7229166-B2 Image-forming method, image-forming apparatus, ink set, and ink CANON KABUSHIKI KAISHA (JP) 2007-06-12 — — US disclosed
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