Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 5/20 | 0.63 |
| ▸ | RAD52 | P43351 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | SLC2A1 | P11166 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 3/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28158394 | 0.84 | POLB (0.68) | POLBRAD52KMT2AKDM4ERAB9A | |
| SCHEMBL7880366 | 0.83 | POLB (0.78) | POLBRAD52KMT2AKDM4ERAB9A | |
| SCHEMBL9748474 | 0.81 | POLB (0.70) | POLBRAD52KMT2AKDM4ERAB9A | |
| SCHEMBL559637 | 0.80 | SLC2A1 (0.72) | POLBRAD52KMT2AKDM4ERAB9A | |
| SCHEMBL7869214 | 0.79 | POLB (0.79) | POLBRAD52KMT2AKDM4ERAB9A | |
| SCHEMBL8608662 | 0.79 | POLB (0.63) | POLBRAD52KMT2AKDM4ERAB9A | |
| SCHEMBL5578493 | 0.79 | POLB (0.79) | POLBRAD52KMT2AKDM4ERAB9A | |
| SCHEMBL617240 | 0.79 | POLB (0.66) | POLBRAD52KMT2AKDM4ERAB9A | |
| SCHEMBL30253677 | 0.79 | POLB (0.66) | POLBRAD52KMT2AKDM4ERAB9A | |
| SCHEMBL9415866 | 0.78 | SLC2A1 (0.75) | POLBRAD52KMT2AKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111018782-B | Preparation method of 9-aminoacridine and derivatives thereof | 郑州本质医药科技有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-111018782-A | Preparation method of 9-aminoacridine and derivatives thereof | 郑州本质医药科技有限公司 | 2020-04-17 | — | — | CN | disclosed |
| WO-2017102934-A1 | VISUAL DETECTION OF PLATINATED DNA LESIONS FROM A CLICKABLE CISPLATIN PROBE USED AS DIAGNOSTIC TOOL OR TO IDENTIFY SYNERGISTIC TREATMENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017005822-A1 | FUNCTIONALIZABLE MOLECULAR PROBE FOR X-RAY FLUORESCENCE IMAGING AND MULTIMODAL IMAGING | PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) | 2017-01-12 | — | — | WO | disclosed |
| US-20140151548-A1 | MATRIX FOR MALDI MASS SPECTROMETRY AND MALDIMASS SPECTROMETRY METHOD | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-20140151548-A1 | MATRIX FOR MALDI MASS SPECTROMETRY AND MALDIMASS SPECTROMETRY METHOD | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| US-7232663-B2 | Assays employing novel substrates for measuring P450-mediated N-dealkylation | THE UNIVERSITY OF WYOMING (US) | 2007-06-19 | — | — | US | disclosed |
| US-7232663-B2 | Assays employing novel substrates for measuring P450-mediated N-dealkylation | THE UNIVERSITY OF WYOMING (US) | 2007-06-19 | — | — | US | disclosed |
| US-20070015235-A1 | Assays employing novel substrates for measuring P450-mediated N-dealkylation | UNIVERSITY OF WYOMING, THE | 2007-01-18 | — | — | US | disclosed |
| US-20070015235-A1 | Assays employing novel substrates for measuring P450-mediated N-dealkylation | UNIVERSITY OF WYOMING, THE | 2007-01-18 | — | — | US | disclosed |