Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.70 |
| ▸ | RAD52 | P43351 | 3/20 | 0.70 |
| ▸ | SLC2A1 | P11166 | 9/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.69 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TTR | P02766 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | TOP2A | P11388 | 4/20 | 0.62 |
| ▸ | ACP1 | P24666 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | ELANE | P08246 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL559637 | 0.95 | SLC2A1 (0.72) | POLBRAD52SLC2A1RAB9ANPC1 | |
| SCHEMBL9415866 | 0.93 | SLC2A1 (0.75) | POLBRAD52SLC2A1RAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL8651166 | 0.92 | SLC2A1 (0.78) | POLBRAD52SLC2A1RAB9ANPC1 | |
| SCHEMBL28158394 | 0.89 | POLB (0.68) | POLBRAD52SLC2A1RAB9ANPC1 | |
| SCHEMBL7869214 | 0.89 | POLB (0.79) | POLBRAD52SLC2A1RAB9ANPC1 | |
| SCHEMBL5578493 | 0.89 | POLB (0.79) | POLBRAD52SLC2A1RAB9ANPC1 | |
| SCHEMBL6033155 | 0.87 | POLB (0.77) | POLBRAD52SLC2A1RAB9ANPC1 | |
| SCHEMBL13856923 | 0.87 | POLB (0.77) | POLBRAD52SLC2A1RAB9ANPC1 | |
| SCHEMBL7880366 | 0.85 | POLB (0.78) | POLBRAD52SLC2A1RAB9ANPC1 | |
| SCHEMBL15867122 | 0.84 | POLB (0.68) | POLBRAD52SLC2A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175172-A | Administering amino-1,2,3,4-tetrahydroacridine and derivatives for elevation of T4 lymphocytes level in patients | DIETLIN FRANCOIS (FR) | 1992-12-29 | — | — | US | disclosed |