Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 20/20 | 0.64 |
| ▸ | THRA | P10827 | 15/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14489192 | 0.91 | THRB (0.70) | THRBTHRA | |
| SCHEMBL14489276 | 0.89 | THRB (0.64) | THRBTHRA | |
| SCHEMBL14489190 | 0.85 | THRB (0.66) | THRBTHRA | |
| SCHEMBL5396846 | 0.80 | THRB (0.74) | THRBTHRA | |
| SCHEMBL5402551 | 0.78 | THRA (1.00) | THRBTHRA | |
| SCHEMBL14488941 | 0.78 | THRB (0.62) | THRBTHRA | |
| SCHEMBL5391484 | 0.77 | THRB (0.70) | THRBTHRA | |
| SCHEMBL5400002 | 0.77 | THRA (0.98) | THRBTHRA | |
| SCHEMBL14488978 | 0.77 | THRB (0.70) | THRBTHRA | |
| SCHEMBL5411272 | 0.77 | THRB (0.82) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7230031-B2 | Thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-06-12 | — | — | US | disclosed |
| US-7230031-B2 | Thyroid hormone receptor ligand, medicinal compositions containing the same and use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2007-06-12 | — | — | US | disclosed |