Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894981 | 0.84 | L3MBTL1 (0.67) | L3MBTL1TSHRHPGDMAPTRECQL | |
| SCHEMBL14489595 | 0.82 | L3MBTL1 (0.51) | L3MBTL1TSHRHPGDALDH1A1MAPT | |
| SCHEMBL2933466 | 0.81 | HPGD (0.66) | L3MBTL1TSHRHPGDALDH1A1MAPT | |
| SCHEMBL1425543 | 0.81 | HPGD (0.66) | L3MBTL1TSHRHPGDALDH1A1MAPT | |
| SCHEMBL6738518 | 0.81 | TSHR (0.96) | TSHRHPGDALDH1A1MAPTKDM4E | |
| SCHEMBL13081206 | 0.81 | HPGD (0.60) | L3MBTL1TSHRHPGDALDH1A1MAPT | |
| SCHEMBL23747579 | 0.80 | CHRM1 (0.63) | NPC1 | |
| SCHEMBL7401505 | 0.80 | HPGD (0.69) | L3MBTL1TSHRHPGDALDH1A1MAPT | |
| SCHEMBL9612077 | 0.79 | TSHR (1.00) | TSHRHPGDALDH1A1MAPTKDM4E | |
| SCHEMBL3936704 | 0.79 | TSHR (1.00) | TSHRHPGDALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007065093-A2 | PYRROLIDINEANILINES | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |