Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30137244 | 0.83 | HRH3 (0.51) | L3MBTL1LMNAALDH1A1TSHRHTT | |
| SCHEMBL14489581 | 0.82 | L3MBTL1 (0.73) | L3MBTL1LMNAALDH1A1TSHRMAPT | |
| SCHEMBL30137230 | 0.81 | HRH3 (0.50) | L3MBTL1LMNAALDH1A1TSHRHPGD | |
| SCHEMBL2846266 | 0.74 | L3MBTL1 (0.38) | L3MBTL1LMNAALDH1A1GAAMAPT | |
| SCHEMBL198598 | 0.73 | TAAR1 (0.50) | ALDH1A1HTT | |
| SCHEMBL105528 | 0.71 | TAAR1 (0.48) | ALDH1A1 | |
| SCHEMBL27804764 | 0.71 | TAAR1 (0.48) | ALDH1A1 | |
| SCHEMBL10602252 | 0.70 | L3MBTL1 (0.52) | L3MBTL1LMNAALDH1A1LSS | |
| SCHEMBL8113789 | 0.70 | RECQL (0.64) | — | |
| SCHEMBL3135932 | 0.70 | TAAR1 (0.46) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007065093-A2 | PYRROLIDINEANILINES | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |